[HTML][HTML] Exosomes as mediators of intercellular crosstalk in metabolism
Exosomes are nanoparticles secreted by all cell types and are a large component of the
broader class of nanoparticles termed extracellular vesicles (EVs). Once secreted …
broader class of nanoparticles termed extracellular vesicles (EVs). Once secreted …
[HTML][HTML] Review of the isolation, characterization, biological function, and multifarious therapeutic approaches of exosomes
Exosomes are extracellular vesicles that contain a specific composition of proteins, lipids,
RNA, and DNA. They are derived from endocytic membranes and can transfer signals to …
RNA, and DNA. They are derived from endocytic membranes and can transfer signals to …
Stroke–heart syndrome: recent advances and challenges
After ischemic stroke, there is a significant burden of cardiovascular complications, both in
the acute and chronic phase. Severe adverse cardiac events occur in 10% to 20% of …
the acute and chronic phase. Severe adverse cardiac events occur in 10% to 20% of …
[HTML][HTML] Extracellular vesicles as signaling mediators and disease biomarkers across biological barriers
Extracellular vesicles act as shuttle vectors or signal transducers that can deliver specific
biological information and have progressively emerged as key regulators of organized …
biological information and have progressively emerged as key regulators of organized …
[HTML][HTML] Systemic exosomal miR-193b-3p delivery attenuates neuroinflammation in early brain injury after subarachnoid hemorrhage in mice
N Lai, D Wu, T Liang, P Pan, G Yuan, X Li, H Li… - Journal of …, 2020 - Springer
Background Inflammation is a potential crucial factor in the pathogenesis of subarachnoid
hemorrhage (SAH). Circulating microRNAs (miRNAs) are involved in the regulation of …
hemorrhage (SAH). Circulating microRNAs (miRNAs) are involved in the regulation of …
Blood-brain barrier dysfunction in normal aging and neurodegeneration: mechanisms, impact, and treatments
AV Andjelkovic, M Situ, AF Citalan-Madrid… - Stroke, 2023 - Am Heart Assoc
Cerebral endothelial cells and their linking tight junctions form a unique, dynamic and multi-
functional interface, the blood-brain barrier (BBB). The endothelium is regulated by …
functional interface, the blood-brain barrier (BBB). The endothelium is regulated by …
[HTML][HTML] Research progress on the role of extracellular vesicles in neurodegenerative diseases
Z Li, X Wang, X Wang, X Yi, YK Wong, J Wu… - Translational …, 2023 - Springer
Neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease,
amyotrophic lateral sclerosis, and Huntington's disease, affect millions of people worldwide …
amyotrophic lateral sclerosis, and Huntington's disease, affect millions of people worldwide …
[HTML][HTML] Repurposing antiviral protease inhibitors using extracellular vesicles for potential therapy of COVID-19
S Kumar, K Zhi, A Mukherji, K Gerth - Viruses, 2020 - mdpi.com
In January 2020, Chinese health agencies reported an outbreak of a novel coronavirus-2
(CoV-2) which can lead to severe acute respiratory syndrome (SARS). The virus, which …
(CoV-2) which can lead to severe acute respiratory syndrome (SARS). The virus, which …
Extracellular vesicles as an emerging frontier in spinal cord injury pathobiology and therapy
Extracellular vesicles (EVs) are membrane-delimited particles that are secreted by nearly all
cell types. EVs mediate crucial physiological functions and pathophysiological processes in …
cell types. EVs mediate crucial physiological functions and pathophysiological processes in …
[HTML][HTML] The barrier and interface mechanisms of the brain barrier, and brain drug delivery
S Zhang, L Gan, F Cao, H Wang, P Gong, C Ma… - Brain Research …, 2022 - Elsevier
Three different barriers are formed between the cerebrovascular and the brain parenchyma:
the blood-brain barrier (BBB), the blood-cerebrospinal fluid barrier (BCSFB), and the …
the blood-brain barrier (BBB), the blood-cerebrospinal fluid barrier (BCSFB), and the …