Dementia is a leading cause of disability and death worldwide. At present there is no
disease modifying treatment for any of the most common types of dementia such as …

Neuroinflammation plays a major role in the etiopathology of neurodegenerative diseases,
including Alzheimer and Parkinson diseases, frontotemporal lobar degeneration, and …

The development of dementia is a devastating aspect of Parkinson's disease (PD), affecting
nearly half of patients within 10 years post-diagnosis. For effective therapies to prevent and …

Dementia with Lewy bodies (DLB) is clinically defined by the presence of visual
hallucinations, fluctuations, rapid eye movement (REM) sleep behavioral disorder, and …

Introduction Tau-targeted positron emission tomography (tau-PET) is a potential tool for the
differential diagnosis of Alzheimer's disease (AD) and to clarify the distribution of tau …

Introduction: To identify individuals with preclinical cognitive impairment, researchers
proposed the concept of objectively-defined subtle cognitive decline (Obj-SCD). However, it …

Purpose The prototypical TSPO radiotracer (R)-[11C] PK11195 has been used in humans
for more than thirty years to visualize neuroinflammation in several pathologies. Alternative …

Dementia with Lewy bodies (DLB) is the second most common neurodegenerative cause of
dementia, behind Alzheimer's disease (AD). The profile of inflammation in AD has been …

Dementia with Lewy bodies (DLB) is a neurodegenerative condition often co-occurring with
Alzheimer's disease (AD) pathology. Characterizing white matter tissue microstructure using …

Posterior cortical atrophy (PCA) and logopenic progressive aphasia (LPA) are clinical
syndromes that commonly have underlying Alzheimer's disease (AD), although non-AD …