Despite continuous improvements in delivery systems, the development of methods for
efficient and specific delivery of targeted therapeutic agents still remains an issue in …

The development of safe, efficient and controllable gene-delivery vectors has become a
bottleneck to human gene therapy. Synthetic polymeric vectors, although safer than viral …

Abstract Poly (amido‐amine) s (PAAs) are synthetic tert‐amino polymers obtained by
stepwise polyaddition of primary or secondary aliphatic amines to bis (acrylamide) s. Linear …

A novel synthesis route toward multifunctional, sequence-defined polyamides is described.
A fully automated, solid-phase supported polymer synthesis was developed and utilized to …

Poly (amidoamine) s (PAAs) are a family of synthetic polymers obtained by stepwise
polyaddition of prim‐or sec‐amines to bisacrylamides. Nearly all conceivable …

The term ribosome-inactivating protein (RIP) is used to denominate proteins mostly of plant
origin, which have N-glycosidase enzymatic activity leading to a complete destruction of the …

Current malaria therapeutics demands strategies able to selectively deliver drugs to
Plasmodium-infected red blood cells (pRBCs) in order to limit the appearance of parasite …

Cancer is one of the most common devastating disease affecting millions of people per year
worldwide. To fight against cancer, a number of natural plant compounds have been …

Antimicrobial peptide drugs are increasingly attractive therapeutic agents as their roles in
physiopathological processes are being unraveled and because the development of …

The toxic moiety of almost all protein-based targeted toxins must enter the cytosol of the
target cell to mediate its fatal effect. Although more than 500 targeted toxins have been …