AGA clinical practice update on endoscopic surveillance and management of colorectal dysplasia in inflammatory bowel diseases: expert review
SK Murthy, JD Feuerstein, GC Nguyen, FS Velayos - Gastroenterology, 2021 - Elsevier
Improvements in disease management, as well as endoscopic technology and quality, have
dramatically changed the way in which we conceptualize and manage inflammatory bowel …
dramatically changed the way in which we conceptualize and manage inflammatory bowel …
[HTML][HTML] Mirikizumab as induction and maintenance therapy for ulcerative colitis
G D'Haens, M Dubinsky, T Kobayashi… - … England Journal of …, 2023 - Mass Medical Soc
Background Mirikizumab, a p19-directed antibody against interleukin-23, showed efficacy in
the treatment of ulcerative colitis in a phase 2 trial. Methods We conducted two phase 3 …
the treatment of ulcerative colitis in a phase 2 trial. Methods We conducted two phase 3 …
ECCO guidelines on therapeutics in ulcerative colitis: medical treatment
Ulcerative colitis [UC] is a chronic inflammatory bowel disease [IBD] characterised by colonic
inflammation extending to a variable extent from the rectum. Care of the patient with UC …
inflammation extending to a variable extent from the rectum. Care of the patient with UC …
Microbiota metabolite butyrate constrains neutrophil functions and ameliorates mucosal inflammation in inflammatory bowel disease
G Li, J Lin, C Zhang, H Gao, H Lu, X Gao, R Zhu… - Gut …, 2021 - Taylor & Francis
Host-microbial cross-talk plays a crucial role in maintenance of gut homeostasis. However,
how microbiota-derived metabolites, eg, butyrate, regulate functions of neutrophils in the …
how microbiota-derived metabolites, eg, butyrate, regulate functions of neutrophils in the …
PICaSSO Histologic Remission Index (PHRI) in ulcerative colitis: development of a novel simplified histological score for monitoring mucosal healing and predicting …
Histological remission is evolving as an important treatment target in UC. We aimed to
develop a simple histological index, aligned to endoscopy, correlated with clinical outcomes …
develop a simple histological index, aligned to endoscopy, correlated with clinical outcomes …
Breaking the therapeutic ceiling in drug development in ulcerative colitis
D Alsoud, B Verstockt, C Fiocchi… - The lancet …, 2021 - thelancet.com
Increased knowledge of the intricate pathogenesis of ulcerative colitis has triggered an
advance in drug development during the past two decades, resulting in the advent of several …
advance in drug development during the past two decades, resulting in the advent of several …
[HTML][HTML] Artificial intelligence enabled histological prediction of remission or activity and clinical outcomes in ulcerative colitis
Background & Aims Microscopic inflammation has significant prognostic value in ulcerative
colitis (UC); however, its assessment is complex with high interobserver variability. We …
colitis (UC); however, its assessment is complex with high interobserver variability. We …
An international consensus to standardize integration of histopathology in ulcerative colitis clinical trials
Background & Aims Histopathology is an emerging treatment target in ulcerative colitis (UC)
clinical trials. Our aim was to provide guidance on standardizing biopsy collection protocols …
clinical trials. Our aim was to provide guidance on standardizing biopsy collection protocols …
中医药治疗溃疡性结肠炎的研究进展述评
张声生， 赵鲁卿 - 北京中医药, 2023 - bjtcm.net
溃疡性结肠炎是一种炎症性肠病, 发病机制尚不明确, 不仅是国际医学领域的难题,
也是我国重点攻关疾病. 中医药治疗UC 具有一定的特色和优势, 内服和外治的多种方法为UC …
也是我国重点攻关疾病. 中医药治疗UC 具有一定的特色和优势, 内服和外治的多种方法为UC …