Matrigel, a basement-membrane matrix extracted from Engelbreth–Holm–Swarm mouse
sarcomas, has been used for more than four decades for a myriad of cell-culture …

In the last ten years, there has been a dramatic surge in the number of publications where
single or groups of cells are grown in substrata that have elements of basement membrane …

Chemoresistance is a leading cause of morbidity and mortality in cancer and it continues to
be a challenge in cancer treatment. Chemoresistance is influenced by genetic and …

The extracellular matrix (ECM) is a ubiquitous member of the body and is key to the
maintenance of tissue and organ integrity. Initially thought to be a bystander in many cellular …

Laminins are large molecular weight glycoproteins constituted by the assembly of three
disulfide-linked polypeptides, the α, β and γ chains. The human genome encodes 11 …

The basement membrane extracellular matrix contacts epithelial, endothelial, fat and smooth
muscle cells. Because this extracellular matrix is so thin, it had been hard to study its …

Basement membranes provide structural support to epithelium, endothelium, muscles, fat
cells, Schwann cells, and axons. Basement membranes are multifunctional: they modulate …

In recent years, the basement membrane (BM)—a specialized form of extracellular matrix
(ECM)—has been recognized as an important regulator of cell behaviour, rather than just a …

Based on the existing literature, a model is presented that postulates a “dynamic reciprocity”
between the extracellular matrix (ECM) on the one hand and the cytoskeleton and the …

During the past 2 decades, mucormycosis has become the third most common invasive
fungal infection in patients with hematological malignancies and organ transplantations [1] …