Abstract Lynch, MA. Long-Term Potentiation and Memory. Physiol Rev 84: 87–136, 2004;
10.1152/physrev. 00014.2003.—One of the most significant challenges in neuroscience is to …

Transcription is a molecular requisite for long-term synaptic plasticity and long-term memory
formation. Thus, in the last several years, one main interest of molecular neuroscience has …

The mitogen‐activated protein kinase (MAP kinase, MAPK) cascade, as the name implies,
was originally discovered as a critical regulator of cell division and differentiation. As further …

The induction of long-term potentiation (LTP) in the dentate gyrus of the hippocampus is
associated with a rapid and robust transcription of the immediate early gene Zif268. We …

In this review we describe an emerging understanding of the roles of the Extracellular-signal
regulated kinase/mitogen-activated protein kinase (ERK/MAPK) cascade in learning and …

There has been nearly a century of interest in the idea that encoding and storage of
information in the brain requires changes in the efficacy of synaptic connections between …

The transcription of the immediate-early genes Arc and Homer 1a (H1a) is dynamically
regulated in response to synaptic activity; their protein products function at the postsynaptic …

The capacity to remember our past experiences and organize our future draws on a number
of cognitive processes that allow our brain to form and store neural representations that can …

From an evolutionary point of view, one of the most important forms of memory is taste-
recognition memory. When an animal eats, food-related cues are associated with the …

The immediate early genes (IEGs) are activated rapidly and transiently in response to a
multitude of stimuli. The zif268 belongs to a category of regulatory IEGs that activate …