The Continuing Threat of Methicillin-Resistant Staphylococcus aureus

M Gajdács - Antibiotics, 2019 - mdpi.com
Staphylococcus aureus has been an exceptionally successful pathogen, which is still
relevant in modern age-medicine due to its adaptability and tenacity. This bacterium may be …

Mechanisms of Resistance to Macrolide Antibiotics among Staphylococcus aureus

M Miklasińska-Majdanik - Antibiotics, 2021 - mdpi.com
Methicillin resistant Staphylococcus aureus strains pose a serious treatment problem
because of their multi-drug resistance (MDR). In staphylococcal strains, resistance to …

Effect of vancomycin or daptomycin with vs without an antistaphylococcal β-lactam on mortality, bacteremia, relapse, or treatment failure in patients with MRSA …

SYC Tong, DC Lye, D Yahav, A Sud, JO Robinson… - Jama, 2020 - jamanetwork.com
Importance Methicillin-resistantStaphylococcus aureus (MRSA) bacteremia is associated
with mortality of more than 20%. Combining standard therapy with a β-lactam antibiotic has …

Antibiotic combination therapy against resistant bacterial infections: synergy, rejuvenation and resistance reduction

ARM Coates, Y Hu, J Holt, P Yeh - Expert review of Anti-infective …, 2020 - Taylor & Francis
ABSTRACT Introduction: Anti-Microbial Resistance (AMR) is a pandemic which threatens
modern medicine. There is a lack of effective drug treatment due to the slow pace, high cost …

Daptomycin

M Heidary, AD Khosravi, S Khoshnood… - Journal of …, 2018 - academic.oup.com
Daptomycin is a cyclic lipopeptide antibiotic used for the treatment of Gram-positive
infections including complicated skin and skin structure infections, right-sided infective …

Clinical data on daptomycin plus ceftaroline versus standard of care monotherapy in the treatment of methicillin-resistant Staphylococcus aureus bacteremia

M Geriak, F Haddad, K Rizvi, W Rose… - Antimicrobial agents …, 2019 - Am Soc Microbiol
Vancomycin (VAN) and daptomycin (DAP) are approved as a monotherapy for methicillin-
resistant Staphylococcus aureus (MRSA) bacteremia. A regimen of daptomycin plus …

Current therapies and challenges for the treatment of Staphylococcus aureus biofilm‐related infections

NN Tran, T Morrisette, SCJ Jorgensen… - … : The Journal of …, 2023 - Wiley Online Library
Staphylococcus aureus is a major cause of nosocomial and community‐acquired infections
and contributes to significant increase in morbidity and mortality especially when associated …

Combined effects of quercetin and curcumin on anti-inflammatory and antimicrobial parameters in vitro

M Güran, G Şanlıtürk, NR Kerküklü, EM Altundağ… - European Journal of …, 2019 - Elsevier
In this in-vitro study, combinatory anti-inflammatory interactions between Quercetin (Q) and
Curcumin (C) along with their combined antimicrobial activity against MRSA were studied …

Treatment strategies for persistent methicillin‐resistant Staphylococcus aureus bacteraemia

PO Lewis, EL Heil, KL Covert… - Journal of clinical …, 2018 - Wiley Online Library
What is known and objective Treatment of methicillin‐resistant Staphylococcus aureus
(MRSA) bacteraemia is a long‐standing challenge to health care, often complicated by …

Adjunctive Daptomycin in the Treatment of Methicillin-susceptible Staphylococcus aureus Bacteremia: A Randomized, Controlled Trial

MP Cheng, A Lawandi, G Butler-Laporte… - Clinical Infectious …, 2021 - academic.oup.com
Abstract Background Bloodstream infections (BSIs) with methicillin-susceptible
Staphylococcus aureus (MSSA) are associated with significant morbidity and mortality. Our …