The gastrointestinal (GI) tract is a system of organs within multicellular animals which
facilitates the ingestion, digestion, and absorption of food with subsequent defecation of …

The maintenance of gastrointestinal (GI) mucosal integrity depends on the rapid alarm of
protective mechanisms in the face of pending injury. Two populations of extrinsic primary …

Nociceptive afferents innervate the stomach and send signals centrally to the brain and
locally to stomach tissues. Nociceptive afferents can be detected with a variety of different …

Gastric ulceration, a focal tissue damage accompanied by inflammation, can influence other
parts of the stomach. Substance P and its receptors are strongly involved in regulation of …

It has been shown that capsaicin-sensitive afferent fibers play a crucial role in acute
gastroprotection. Release of neurotransmitters such as calcitonin gene-related peptide …

Acute gastritis is often untreatable by acid secretion-inhibiting drugs. Understanding the
protective mechanisms including the role of Transient Receptor Potential Ankyrin1 (TRPA1) …

It is suggested that different neuropeptides regulate gastric mucosal integrity and participate
in the development of chronic gastritis. The aim of this study was to examine the roles and …

The aim of this study was to investigate the protective action of rice extract on ethanol-
induced mucosal damage in vivo and wound healing of epithelial cells in vitro. Also, the …

Laboratory of Experimental Endocrinology, Pavlov Institute of Physiology, Russian Academy
of Sciences, St. Petersburg, Russia capsaicin-sensitive sensory nerves are densely …

Resiniferatoxin (RTX), an extract from the spurge plant Euphorbia resinifera, is a potent
agonist of the transient receptor potential cation channel subfamily V member 1 (TRPV1) …