Molecular mechanism of heavy metals (Lead, Chromium, Arsenic, Mercury, Nickel and Cadmium)-induced hepatotoxicity–A review
K Renu, R Chakraborty, H Myakala, R Koti… - Chemosphere, 2021 - Elsevier
Heavy metals pose a serious threat if they go beyond permissible limits in our bodies. Much
heavy metal's viz. Lead, Chromium, Arsenic, Mercury, Nickel, and Cadmium pose a serious …
heavy metal's viz. Lead, Chromium, Arsenic, Mercury, Nickel, and Cadmium pose a serious …
Rutin ameliorates inflammation and improves metabolic function: A comprehensive analysis of scientific literature
N Muvhulawa, PV Dludla, K Ziqubu… - Pharmacological …, 2022 - Elsevier
Chronic inflammation remains an essential complication in the pathogenesis and
aggravation of metabolic diseases. There is a growing interest in the use of medicinal plants …
aggravation of metabolic diseases. There is a growing interest in the use of medicinal plants …
Protective effects of microbiome-derived inosine on lipopolysaccharide-induced acute liver damage and inflammation in mice via mediating the TLR4/NF-κB pathway
W Guo, Q Xiang, B Mao, X Tang, S Cui… - Journal of agricultural …, 2021 - ACS Publications
This research assessed the anti-inflammatory and hepatoprotective properties of inosine
and the associated mechanism. Inosine pretreatment significantly reduced the secretion of …
and the associated mechanism. Inosine pretreatment significantly reduced the secretion of …
Protective effects of chrysin against oxidative stress and inflammation induced by lead acetate in rat kidneys: a biochemical and histopathological approach
In this study, the protective effects of chrysin (CR) on lead acetate (PbAc)-induced renal
toxicity in Sprague-Dawley rats were investigated with biochemical, histopathological, and …
toxicity in Sprague-Dawley rats were investigated with biochemical, histopathological, and …
Beneficial effects of Chrysin on Cadmium‐induced nephrotoxicity in rats: Modulating the levels of Nrf2/HO‐1, RAGE/NLRP3, and Caspase-3/Bax/Bcl-2 signaling …
Cadmium (Cd) is a toxic heavy metal that targets the kidney directly in the body. Chrysin
(CHR) is a natural flavonoid with many properties such as antioxidant, anti-inflammatory and …
(CHR) is a natural flavonoid with many properties such as antioxidant, anti-inflammatory and …
Protective effects of morin against acrylamide-induced hepatotoxicity and nephrotoxicity: A multi-biomarker approach
Acrylamide (ACR) is a heat-induced carcinogen substance that is found in some foods due
to cooking or other thermal processes. The aim of present study was to assess the probable …
to cooking or other thermal processes. The aim of present study was to assess the probable …
Hesperidin protects against the chlorpyrifos‐induced chronic hepato‐renal toxicity in rats associated with oxidative stress, inflammation, apoptosis, autophagy, and up …
In this study, we investigated the effects of hesperidin (HSP) on oxidants/antioxidants status,
inflammation, apoptotic, and autophagic activity in hepato‐renal toxicity induced by chronic …
inflammation, apoptotic, and autophagic activity in hepato‐renal toxicity induced by chronic …
Evaluation of protective effects of quercetin against cypermethrin‐induced lung toxicity in rats via oxidative stress, inflammation, apoptosis, autophagy, and …
M Ileriturk, O Kandemir… - Environmental …, 2022 - Wiley Online Library
Cypermethrin (CYP), a type II synthetic pyrethroid, is the most widely used insecticide
worldwide. Inhalation of it may cause side effects. This study is aimed to examine potential …
worldwide. Inhalation of it may cause side effects. This study is aimed to examine potential …
Protective effect of chrysin on cyclophosphamide-induced hepatotoxicity and nephrotoxicity via the inhibition of oxidative stress, inflammation, and apoptosis
Cyclophosphamide (CYP) is a chemotherapeutic agent used in the treatment of autoimmune
disorders and malignant diseases. However, its usage is restricted due to its severe side …
disorders and malignant diseases. However, its usage is restricted due to its severe side …
Rutin protects rat liver and kidney from sodium valproate-induce damage by attenuating oxidative stress, ER stress, inflammation, apoptosis and autophagy
Background The present study investigated the effects of rutin (RUT), which has various
biological and pharmacological properties, on liver and kidney damage caused by histone …
biological and pharmacological properties, on liver and kidney damage caused by histone …