Optical coherence tomography and glaucoma

A Geevarghese, G Wollstein, H Ishikawa… - Annual review of …, 2021 - annualreviews.org
Early detection and monitoring are critical to the diagnosis and management of glaucoma, a
progressive optic neuropathy that causes irreversible blindness. Optical coherence …

Discovery and clinical translation of novel glaucoma biomarkers

G Beykin, AM Norcia, VJ Srinivasan, A Dubra… - Progress in Retinal and …, 2021 - Elsevier
Glaucoma and other optic neuropathies are characterized by progressive dysfunction and
loss of retinal ganglion cells and their axons. Given the high prevalence of glaucoma-related …

Ocular blood flow in glaucoma–the Leuven Eye Study

L Abegão Pinto, K Willekens, K Van Keer… - Acta …, 2016 - Wiley Online Library
Purpose Elevated intra‐ocular pressure (IOP) has been identified as a major risk factor for
glaucoma. Additionally, extensive literature depicts a vascular dysfunction to exist in these …

Retinal oximetry: metabolic imaging for diseases of the retina and brain

E Stefánsson, OB Olafsdottir, TS Eliasdottir… - Progress in retinal and …, 2019 - Elsevier
Retinal oximetry imaging of retinal blood vessels measures oxygen saturation of
hemoglobin. The imaging technology is non-invasive and reproducible with remarkably low …

Ocular blood flow as a clinical observation: Value, limitations and data analysis

A Harris, G Guidoboni, B Siesky, S Mathew… - Progress in retinal and …, 2020 - Elsevier
Alterations in ocular blood flow have been identified as important risk factors for the onset
and progression of numerous diseases of the eye. In particular, several population-based …

[HTML][HTML] Advances in retinal oximetry

AK Garg, D Knight, L Lando… - … Vision Science & …, 2021 - iovs.arvojournals.org
Similar to other organs, the retina relies on tightly regulated perfusion and oxygenation.
Previous studies have demonstrated that retinal blood flow is affected in a variety of eye and …

[HTML][HTML] Retinal oximetry discovers novel biomarkers in retinal and brain diseases

E Stefánsson, OB Olafsdottir… - … & visual science, 2017 - iovs.arvojournals.org
Purpose: Biomarkers for several eye and brain diseases are reviewed, where retinal
oximetry may help confirm diagnosis or measure severity of disease. These include diabetic …

[HTML][HTML] Retinal oxygen metabolism during normoxia and hyperoxia in healthy subjects

S Palkovits, M Lasta, R Told, D Schmidl… - … & visual science, 2014 - jov.arvojournals.org
Methods.: Forty-six healthy subjects were included in the present study, and data of 41
subjects could be evaluated. Retinal vessel diameters, as well as oxygen saturation in …

[HTML][HTML] Retinal oxygen metabolism in patients with mild cognitive impairment

OB Olafsdottir, HS Saevarsdottir, SH Hardarson… - Alzheimer's & Dementia …, 2018 - Elsevier
Introduction We have previously reported that retinal vessel oxygen saturation is increased
in mild-to-moderate dementia of Alzheimer's type when compared with healthy individuals …

Improved discrimination between normal‐tension and primary open‐angle glaucoma with advanced vascular examinations–the Leuven Eye Study

J Barbosa‐Breda, K Van Keer… - Acta …, 2019 - Wiley Online Library
Purpose Vascular factors have been suggested to influence the development and
progression of glaucoma. They are thought to be especially relevant for normal‐tension …