Abnormal cerebellar development in autism spectrum disorders
ME van der Heijden, JS Gill, RV Sillitoe - Developmental neuroscience, 2021 - karger.com
Autism spectrum disorders (ASD) comprise a group of heterogeneous neurodevelopmental
conditions characterized by impaired social interactions and repetitive behaviors with …
conditions characterized by impaired social interactions and repetitive behaviors with …
Deconstructing sonic hedgehog medulloblastoma: molecular subtypes, drivers, and beyond
Medulloblastoma (MB) is a highly malignant cerebellar tumor predominantly diagnosed
during childhood. Driven by pathogenic activation of sonic hedgehog (SHH) signaling, SHH …
during childhood. Driven by pathogenic activation of sonic hedgehog (SHH) signaling, SHH …
Neoplastic and immune single-cell transcriptomics define subgroup-specific intra-tumoral heterogeneity of childhood medulloblastoma
KA Riemondy, S Venkataraman, N Willard… - Neuro …, 2022 - academic.oup.com
Background Medulloblastoma (MB) is a heterogeneous disease in which neoplastic cells
and associated immune cells contribute to disease progression. We aimed to determine the …
and associated immune cells contribute to disease progression. We aimed to determine the …
High-resolution transcriptional landscape of xeno-free human induced pluripotent stem cell-derived cerebellar organoids
Current protocols for producing cerebellar neurons from human pluripotent stem cells
(hPSCs) often rely on animal co-culture and mostly exist as monolayers, limiting their …
(hPSCs) often rely on animal co-culture and mostly exist as monolayers, limiting their …
The human brain vasculature shows a distinct expression pattern of SARS-CoV-2 entry factors
M Ghobrial, J Charish, S Takada, T Valiante… - BioRxiv, 2020 - biorxiv.org
ABSTRACT A large number of hospitalized COVID-19 patients show neurological symptoms
such as ischemic-and hemorrhagic stroke as well as encephalitis, and SARS-CoV-2 can …
such as ischemic-and hemorrhagic stroke as well as encephalitis, and SARS-CoV-2 can …
More than meets the eye: exploring Sonic Hedgehog medulloblastoma from a neurodevelopmental perspective
I Armandari - 2021 - research.rug.nl
Cerebellar development is a complex process that requires tight orchestration of various
factors to ensure proper cerebellar function. The relatively long time-span for the cerebellum …
factors to ensure proper cerebellar function. The relatively long time-span for the cerebellum …