[HTML][HTML] Transdiagnostic computations of uncertainty: towards a new lens on intolerance of uncertainty

TR Sandhu, B Xiao, RP Lawson - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
People radically differ in how they cope with uncertainty. Clinical researchers describe a
dispositional characteristic known as “intolerance of uncertainty”, a tendency to find …

Psychological mechanisms and functions of 5-HT and SSRIs in potential therapeutic change: Lessons from the serotonergic modulation of action selection, learning …

C Roberts, BJ Sahakian, TW Robbins - Neuroscience & biobehavioral …, 2020 - Elsevier
Uncertainty regarding which psychological mechanisms are fundamental in mediating SSRI
treatment outcomes and wide-ranging variability in their efficacy has raised more questions …

Inattentive responding can induce spurious associations between task behaviour and symptom measures

S Zorowitz, J Solis, Y Niv, D Bennett - Nature human behaviour, 2023 - nature.com
Although online samples have many advantages for psychiatric research, some potential
pitfalls of this approach are not widely understood. Here we detail circumstances in which …

How the discrepancy between prior expectations and new information influences expectation updating in depression—the greater, the better?

T Kube, L Kirchner, G Lemmer… - Clinical Psychological …, 2022 - journals.sagepub.com
Previous research on expectation updating in relation to psychopathology used to treat
expectation-confirming information and expectation-disconfirming information as binary …

Comparable roles for serotonin in rats and humans for computations underlying flexible decision-making

Q Luo, JW Kanen, A Bari, N Skandali… - …, 2024 - nature.com
Serotonin is critical for adapting behavior flexibly to meet changing environmental demands.
Cognitive flexibility is important for successful attainment of goals, as well as for social …

Effect of lysergic acid diethylamide (LSD) on reinforcement learning in humans

JW Kanen, Q Luo, MR Kandroodi… - Psychological …, 2023 - cambridge.org
BackgroundThe non-selective serotonin 2A (5-HT2A) receptor agonist lysergic acid
diethylamide (LSD) holds promise as a treatment for some psychiatric disorders …

[HTML][HTML] Anhedonia and sensitivity to punishment in schizophrenia, depression and opiate use disorder

P Ossola, N Garrett, L Biso, A Bishara… - Journal of Affective …, 2023 - Elsevier
Background From a behavioural perspective anhedonia is defined as diminished interest in
the engagement of pleasurable activities. Despite its presence across a range of psychiatric …

Reviewing explore/exploit decision-making as a transdiagnostic target for psychosis, depression, and anxiety

A Lloyd, JP Roiser, S Skeen, Z Freeman… - Cognitive, Affective, & …, 2024 - Springer
In many everyday decisions, individuals choose between trialling something novel or
something they know well. Deciding when to try a new option or stick with an option that is …

Contextual influence of reinforcement learning performance of depression: evidence for a negativity bias?

H Vandendriessche, A Demmou, S Bavard… - Psychological …, 2023 - cambridge.org
BackgroundsValue-based decision-making impairment in depression is a complex
phenomenon: while some studies did find evidence of blunted reward learning and reward …

How negative mood hinders belief updating in depression: results from two experimental studies

T Kube, L Kirchner, T Gärtner… - Psychological …, 2023 - cambridge.org
Background In two experimental studies, we tested the hypothesis that negative mood would
hinder the revision of negative beliefs in response to unexpectedly positive information in …