The interplay between the commensal microbiota and the mammalian immune system
development and function includes multifold interactions in homeostasis and disease. The …

Over the past decade, our view of human-associated microbes has expanded beyond that of
a few species toward an appreciation of the diverse and niche-specialized microbial …

Antibiotics in childhood have been linked with diseases including asthma, juvenile arthritis,
type 1 diabetes, Crohn's disease and mental illness. The underlying mechanisms are …

It is well established that the gut microbiota plays an important role in host health and is
perturbed by several factors including antibiotics. Antibiotic‐induced changes in microbial …

Neonates at risk of childhood atopy and asthma exhibit perturbation of the gut microbiome,
metabolic dysfunction and increased concentrations of 12, 13-diHOME in their faeces …

Background Antibiotics are amongst the most commonly used drugs in children. In addition
to inducing antibiotic resistance, antibiotic exposure has been associated with adverse long …

In the 21st century, urbanization represents a major demographic shift in developed and
developing countries. Rapid urbanization in the developing world has been associated with …

Increased exposure to antibiotics during early childhood increases the risk of antibiotic-
associated dysbiosis, which is associated with reduced diversity of gut microbial species …

Human gut is colonized by numerous microorganisms, in which bacteria present the highest
proportion of this colonization that live in a symbiotic relationship with the host. This …

Background The prevalence of pediatric allergic diseases has increased rapidly in the
United States over the past few decades. Recent studies suggest an association between …