The native environment of membrane proteins is complex and scientists have felt the need
to simplify it to reduce the number of varying parameters. However, experimental problems …

Linear peptide antibiotics have been isolated from amphibians, insects and humans and
used as templates to design cheaper and more potent analogues for medical applications …

Polymer‐based nanodiscs are valuable tools in biomedical research that can offer a
detergent‐free solubilization of membrane proteins maintaining their native lipid …

Bicelles are a versatile class of model membranes known to align in magnetic fields.
Bicelles were originally developed for use in solid-state NMR studies of …

Revised Manuscript Received January 18, 1995® abstract: This paperdescribes a study
undertaken to assess the possibility and practical consequences of reconstituting integral …

Structure determination by nuclear magnetic resource (NMR) traditionally has relied on the
measurement of a maximum possible number of semiquantitative local restraints. The most …

Protein solution nuclear magnetic resonance (NMR) can be conducted in a slightly
anisotropic environment, where the orientational distribution of the proteins is no longer …

High resolution NMR techniques are now commonly applied to structural analyses of
complex biomolecules.(') However, these techniques have not proved applicable to most …

A third of the genes in prokaryotic and eukaryotic genomes encode membrane proteins that
are either essential for signal transduction and solute transport or function as scaffold …

The chemical shift of a nucleus, i, in a molecule arises from the nuclear shielding effect of an
applied magnetic field, caused by an induced magnetic field resulting from circulation of …