[HTML][HTML] The molecular mechanisms and therapeutic strategies of EMT in tumor progression and metastasis
Y Huang, W Hong, X Wei - Journal of hematology & oncology, 2022 - Springer
Epithelial–mesenchymal transition (EMT) is an essential process in normal embryonic
development and tissue regeneration. However, aberrant reactivation of EMT is associated …
development and tissue regeneration. However, aberrant reactivation of EMT is associated …
[HTML][HTML] Epithelial-mesenchymal plasticity in cancer progression and metastasis
W Lu, Y Kang - Developmental cell, 2019 - cell.com
Epithelial-to-mesenchymal transition (EMT) and its reversed process, mesenchymal-to-
epithelial transition (MET), are fundamental processes in embryonic development and tissue …
epithelial transition (MET), are fundamental processes in embryonic development and tissue …
The role of snail in EMT and tumorigenesis
Y Wang, J Shi, K Chai, X Ying… - Current cancer drug …, 2013 - ingentaconnect.com
Epithelial-mesenchymal transition (EMT) is a highly conserved process in which polarized,
immobile epithelial cells lose tight junctions, associated adherence, and become migratory …
immobile epithelial cells lose tight junctions, associated adherence, and become migratory …
Protein arginine methyltransferases and cancer
Y Yang, MT Bedford - Nature Reviews Cancer, 2013 - nature.com
There are nine protein arginine methyltransferases (PRMTs) encoded in mammalian
genomes, the protein products of which catalyse three types of arginine methylation …
genomes, the protein products of which catalyse three types of arginine methylation …
The PRMT5 arginine methyltransferase: many roles in development, cancer and beyond
N Stopa, JE Krebs, D Shechter - Cellular and molecular life sciences, 2015 - Springer
Post-translational arginine methylation is responsible for regulation of many biological
processes. The protein arginine methyltransferase 5 (PRMT5, also known as Hsl7, Jbp1 …
processes. The protein arginine methyltransferase 5 (PRMT5, also known as Hsl7, Jbp1 …
[HTML][HTML] Central role of Snail1 in the regulation of EMT and resistance in cancer: a target for therapeutic intervention
S Kaufhold, B Bonavida - Journal of Experimental & Clinical Cancer …, 2014 - Springer
Snail1 is the founding member of the Snail superfamily of zinc-finger transcription factors,
which also includes Snail2 (Slug) and Snail3 (Smuc). The superfamily is involved in cell …
which also includes Snail2 (Slug) and Snail3 (Smuc). The superfamily is involved in cell …
Epithelial-to-mesenchymal transition: epigenetic reprogramming driving cellular plasticity
N Skrypek, S Goossens, E De Smedt, N Vandamme… - Trends in Genetics, 2017 - cell.com
Epithelial-to-mesenchymal transition (EMT) is a process in which epithelial cells lose their
junctions and polarity to gain a motile mesenchymal phenotype. EMT is essential during …
junctions and polarity to gain a motile mesenchymal phenotype. EMT is essential during …
Retinoic acid receptors: from molecular mechanisms to cancer therapy
Retinoic acid (RA), the major bioactive metabolite of retinol or vitamin A, induces a spectrum
of pleiotropic effects in cell growth and differentiation that are relevant for embryonic …
of pleiotropic effects in cell growth and differentiation that are relevant for embryonic …
EMT, the cytoskeleton, and cancer cell invasion
M Yilmaz, G Christofori - Cancer and Metastasis Reviews, 2009 - Springer
The metastatic process, ie the dissemination of cancer cells throughout the body to seed
secondary tumors at distant sites, requires cancer cells to leave the primary tumor and to …
secondary tumors at distant sites, requires cancer cells to leave the primary tumor and to …
EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness
E Sánchez-Tilló, Y Liu, O de Barrios, L Siles… - Cellular and molecular …, 2012 - Springer
Cancer is a complex multistep process involving genetic and epigenetic changes that
eventually result in the activation of oncogenic pathways and/or inactivation of tumor …
eventually result in the activation of oncogenic pathways and/or inactivation of tumor …