Epithelial–mesenchymal transition (EMT) is an essential process in normal embryonic
development and tissue regeneration. However, aberrant reactivation of EMT is associated …

Epithelial-to-mesenchymal transition (EMT) and its reversed process, mesenchymal-to-
epithelial transition (MET), are fundamental processes in embryonic development and tissue …

Epithelial-mesenchymal transition (EMT) is a highly conserved process in which polarized,
immobile epithelial cells lose tight junctions, associated adherence, and become migratory …

There are nine protein arginine methyltransferases (PRMTs) encoded in mammalian
genomes, the protein products of which catalyse three types of arginine methylation …

Post-translational arginine methylation is responsible for regulation of many biological
processes. The protein arginine methyltransferase 5 (PRMT5, also known as Hsl7, Jbp1 …

Snail1 is the founding member of the Snail superfamily of zinc-finger transcription factors,
which also includes Snail2 (Slug) and Snail3 (Smuc). The superfamily is involved in cell …

Epithelial-to-mesenchymal transition (EMT) is a process in which epithelial cells lose their
junctions and polarity to gain a motile mesenchymal phenotype. EMT is essential during …

Retinoic acid (RA), the major bioactive metabolite of retinol or vitamin A, induces a spectrum
of pleiotropic effects in cell growth and differentiation that are relevant for embryonic …

The metastatic process, ie the dissemination of cancer cells throughout the body to seed
secondary tumors at distant sites, requires cancer cells to leave the primary tumor and to …

Cancer is a complex multistep process involving genetic and epigenetic changes that
eventually result in the activation of oncogenic pathways and/or inactivation of tumor …