Discovery of sulfonamide-tethered isatin derivatives as novel anticancer agents and VEGFR-2 inhibitors
In this work, new isatin-based sulphonamides (6a-i, 11a-c, 12a-c) were designed and
synthesised as potential dual VEGFR-2 and carbonic anhydrase inhibitors with anticancer …
synthesised as potential dual VEGFR-2 and carbonic anhydrase inhibitors with anticancer …
Andrographolide reverts multidrug resistance in KBChR 8‐5 cells through AKT signaling pathway
DS Lakra, P Bharathiraja… - Cell Biochemistry …, 2024 - Wiley Online Library
Multidrug resistance (MDR) is a major obstacle in cancer chemotherapy. P‐glycoprotein (P‐
gp) one of the ATP‐binding cassette (ABC) transporters plays an important role in MDR. In …
gp) one of the ATP‐binding cassette (ABC) transporters plays an important role in MDR. In …