A visco-poroelastic model of functional adaptation in bones reconstructed with bio-resorbable materials
In this paper, the phenomena of resorption and growth of bone tissue and resorption of the
biomaterial inside a bicomponent system are studied by means of a numerical method …
biomaterial inside a bicomponent system are studied by means of a numerical method …
Mechano-Regulation of Trabecular Bone Adaptation Is Controlled by the Local in vivo Environment and Logarithmically Dependent on Loading Frequency
AC Scheuren, P Vallaster, GA Kuhn… - … in bioengineering and …, 2020 - frontiersin.org
It is well-established that cyclic, but not static, mechanical loading has anabolic effects on
bone. However, the function describing the relationship between the loading frequency and …
bone. However, the function describing the relationship between the loading frequency and …
Predicting cortical bone adaptation to axial loading in the mouse tibia
AF Pereira, B Javaheri… - Journal of the …, 2015 - royalsocietypublishing.org
The development of predictive mathematical models can contribute to a deeper
understanding of the specific stages of bone mechanobiology and the process by which …
understanding of the specific stages of bone mechanobiology and the process by which …
Microstructural changes associated with osteoporosis negatively affect loading-induced fluid flow around osteocytes in cortical bone
V Gatti, EM Azoulay, SP Fritton - Journal of biomechanics, 2018 - Elsevier
Loading-induced interstitial fluid flow in the microporosities of bone is critical for osteocyte
mechanotransduction and for the maintenance of tissue health, enhancing convective …
mechanotransduction and for the maintenance of tissue health, enhancing convective …
In silico modeling of bone adaptation to rest-inserted loading: strain energy density versus fluid flow as stimulus
In vivo studies suggest that cyclic and low-magnitude loading can be useful over
pharmaceutical drugs in normalizing bone loss as it encourages osteogenesis (ie new bone …
pharmaceutical drugs in normalizing bone loss as it encourages osteogenesis (ie new bone …
Viscoelastic properties of rapid prototyped magnetic nanocomposite scaffolds for osteochondral tissue regeneration
Poly (ɛ-caprolactone) and poly (ethylene glycol) based magnetic nanocomposite scaffolds
were fabricated using fused deposition modeling and stereolithography approaches, and a …
were fabricated using fused deposition modeling and stereolithography approaches, and a …
[HTML][HTML] Derivation, validation, and prediction of loading-induced mineral apposition rates at endocortical and periosteal bone surfaces based on fluid velocity and …
The capacity of bone to optimize its structure in response to mechanical loads has been
widely observed. The mechanical load acting on a bone at the macroscopic level influences …
widely observed. The mechanical load acting on a bone at the macroscopic level influences …
Spatiotemporal characterization of microdamage accumulation in rat ulnae in response to uniaxial compressive fatigue loading
X Zhang, X Liu, Z Yan, J Cai, F Kang, S Shan, P Wang… - Bone, 2018 - Elsevier
Repetitive fatigue loading can induce microdamage accumulation in bone matrix, which
results in impaired mechanical properties and increased fracture susceptibility. However, the …
results in impaired mechanical properties and increased fracture susceptibility. However, the …
Anatomical variations in cortical bone surface permeability: tibia versus femur
Cortical bone surfaces (periosteal and endosteal) exhibit differential (re) modelling response
to mechanical loading. This poses a serious challenge in establishing an in silico model to …
to mechanical loading. This poses a serious challenge in establishing an in silico model to …
The role of fluid flow on bone mechanobiology: mathematical modeling and simulation
The effect of fluid flow on tissue adaptation was the focus of many research works during the
last years. Moreover, the use of poroelasticity models to simulate and understand the …
last years. Moreover, the use of poroelasticity models to simulate and understand the …