Short tandem repeats (STRs) are units of 1–6 bp that repeat in a tandem fashion in DNA.
Along with single nucleotide polymorphisms and large structural variations, they are among …

Short tandem repeats (STRs) are abundant and highly mutagenic in the human genome.
Many STR loci have been associated with a range of human genetic disorders. However …

The ribosomal DNA (rDNA) in Drosophila is found as two additive clusters of individual 35 S
cistrons. The multiplicity of rDNA is essential to assure proper translational demands, but the …

The human SBF1 (SET binding factor 1) gene, alternatively known as MTMR5, is
predominantly expressed in the brain, and its epigenetic dysregulation is linked to late-onset …

Although mainly located in genic regions and being mutation hotspots, intact blocks of CG-
rich trinucleotide short tandem repeats (STRs) are largely overlooked with respect to their …

Microbes are evolutionarily robust organisms capable of rapid adaptation to complex stress,
which enables them to colonize harsh environments. In nature, microbes are regularly …

The ribosomal RNA genes (rDNA) are tandemly arrayed in most eukaryotes and exhibit vast
copy number variation. There is growing interest in integrating this variation into genotype …

Evolutionary innovations allow populations to colonize new ecological niches. We
previously reported that aerobic growth on citrate (Cit+) evolved in an Escherichia coli …

Background: Approximately 2% of the human core promoter short tandem repeats (STRs)
reach lengths of≥ 6 repeats, which may in part be a result of adaptive evolutionary …

Background Because of high mutation rate, overrepresentation in genic regions, and link
with various neurological, neurodegenerative, and movement disorders, GGC and GCC …