Strategies to use fibrinogen as bioink for 3D bioprinting fibrin-based soft and hard tissues

BAG de Melo, YA Jodat, EM Cruz, JC Benincasa… - Acta biomaterialia, 2020 - Elsevier
Fibrin gel has been widely used for engineering various types of tissues due to its
biocompatible nature, biodegradability, and tunable mechanical and nanofibrous structural …

Platelet-rich plasma and its derivatives as promising bioactive materials for regenerative medicine: basic principles and concepts underlying recent advances

T Kawase - Odontology, 2015 - Springer
Over the past decade, platelet-rich plasma (PRP), a platelet-concentrated plasma fraction,
has been widely investigated and applied to regenerative medicine. The clinical utility of …

Sustained release of growth factors from photoactivated platelet rich plasma (PRP)

G Irmak, TT Demirtaş, M Gümüşderelioğlu - European Journal of …, 2020 - Elsevier
The goal of this study is to specify the ability of polychromatic light source (PAC), providing
effective wavelengths in the range of 600–1200 nm (near-infrared region, NIR), to activate …

The role of VEGF, PDGF and IL-6 on diabetic foot ulcer after Platelet Rich Fibrin+ hyaluronic therapy

RW Kartika, I Alwi, FD Suyatna, E Yunir, S Waspadji… - Heliyon, 2021 - cell.com
Background Current standard management of diabetic foot ulcers (DFUs) consists of
surgical debridement followed by soak NaCl 0.9% gauzes tight infection and glycaemic …

Fabrication and characterization of platelet-rich plasma scaffolds for tissue engineering applications

M Sadeghi-Ataabadi, Z Mostafavi-Pour… - Materials Science and …, 2017 - Elsevier
Abstract Platelet-Rich Plasma (PRP), as a rich source of growth factor, can form a fibrin gel
that recapitulates the extracellular matrix of the tissues. The aim of this study was to evaluate …

Structural properties of fracture haematoma: current status and future clinical implications

X Wang, T Friis, V Glatt, R Crawford… - Journal of tissue …, 2017 - Wiley Online Library
Blood clots (haematomas) that form immediately following a bone fracture have been shown
to be vital for the subsequent healing process. During the clotting process, a number of …

[HTML][HTML] Hyaluronic acid induces the release of growth factors from platelet-rich plasma

K Iio, KI Furukawa, E Tsuda, Y Yamamoto… - Asia-Pacific Journal of …, 2016 - Elsevier
Abstract Background/Objective Platelet-rich plasma (PRP) and hyaluronic acid (HA)
injection are both therapeutic options for osteoarthritis and chronic tendinopathy. Although …

Wound healing in diabetic foot ulcer patients using combined use of platelet rich fibrin and hyaluronic acid, platelet rich fibrin and placebo: an open label, randomized …

RW Kartika, I Alwi, FD Suyatna, E Yunir… - Acta Medica …, 2021 - actamedindones.org
Background: Autologous platelet-rich fibrin (A-PRF) is an adjunctive method for diabetic foot
ulcer (DFU) in addition to glycaemic control and debridement. This study aimed to evaluate …

Nanofat accelerates and improves the vascularization, lymphatic drainage and healing of full-thickness murine skin wounds

E Limido, A Weinzierl, E Ampofo, Y Harder… - International Journal of …, 2024 - mdpi.com
The treatment of wounds using the body's own resources is a promising approach to support
the physiological regenerative process. To advance this concept, we evaluated the effect of …

Centrifugation conditions in the L-PRP preparation affect soluble factors release and mesenchymal stem cell proliferation in fibrin nanofibers

BAG de Melo, ÂCM Luzo, JFSD Lana, MHA Santana - Molecules, 2019 - mdpi.com
Leukocyte and platelet-rich plasma (L-PRP) is an autologous product that when activated
forms fibrin nanofibers, which are useful in regenerative medicine. As an important part of …