Exercise is an integral part of the rehabilitation of patients suffering a variety of chronic
musculoskeletal conditions, such as fibromyalgia, chronic low back pain and myofascial …

Neuropathic pain is a disease of the somatosensory system that is characterized by tingling,
burning, and/or shooting pain. Medication is often the primary treatment, but it can be costly …

Background Exercise is often prescribed as a therapy for chronic pain. Short-term exercise
briefly increases the production of endogenous analgesics, leading to transient …

Inflammatory pain impacts adversely on the quality of life of patients, often resulting in motor
disabilities. Therefore, we studied the effect of peripheral inflammation induced by …

Chronic musculoskeletal pain is a significant health problem and is associated with
increases in pain during acute physical activity. Regular physical activity is protective …

Physical exercise is a low-cost, safe, and efficient intervention for the reduction of
neuropathic chronic pain in humans. However, the underlying mechanisms for how exercise …

Oxidative stress can be induced by various stimuli and altered in certain conditions,
including exercise and pain. Although many studies have investigated oxidative stress in …

Peripheral nerve injury (PNI) activates the immune system, resulting in increased
proinflammatory cytokines at the site of injury and in the spinal cord dorsal horn. Exercise …

BACKGROUND: The underlying mechanism of exercise on neuropathic pain is not well
understood. We investigated whether physical exercise regulates the functional recovery …

Exercise is known to exert a systemic anti-inflammatory influence, but whether its effects are
sufficient to protect against subsequent neuropathic pain is underinvestigated. We report …