Background: Cisplatin (Cp) is an antineoplastic agent with a dose-limiting nephrotoxicity. Cp-
induced nephrotoxicity is characterized by the interplay of oxidative stress, inflammation …

Background and aim Many attempts to control acute kidney injury (AKI) have failed due to a
lack of understanding of its pathophysiological key components. Macrophages are a crucial …

Broccoli (Brassica oleracea) is reported to possess antioxidant activity that could potentially
prevent oxidative damage to tissues caused by many diseases. In the present study, we …

Background and aim Gentamycin-induced nephrotoxicity is related to stimulation of
oxidative stress and inflammatory cascades leading to apoptotic renal damage. Heme …

The current experiment aimed to identify the possible protective role of rivastigmine (RIVA)
in gentamicin (GNT)-induced acute kidney injury (AKI) in rats. RIVA was administered in the …

Background Cisplatin (CPN) is used in the treatment of various cancers. However, the
especially nephrotoxic effect is limiting its use. We aimed to evaluate the renoprotective …

Gentamicin (GEN) is an aminoglycoside antibiotic used to treat gram-negative bacterial
infections. Our study aimed to explore curcumin's (CMN) protective role against GEN …

Aim Gentamicin-induced nephrotoxicity limits its widespread use as an effective antibacterial
agent. Oxidative stress, inflammatory cytokines and apoptotic cell death are major …

The current study aimed to investigate the ameliorative effects of Artemisia annua (RA)
extract on hepatic toxicity induced by gentamicin injection mice. Sixteen mice were divided …

Gentamicin (Genta)-induced nephrotoxicity poses a significant clinical challenge due to its
detrimental effects on kidney function. Clopidogrel (Clop), an antiplatelet drug known for its …