To execute the intricate process of development, cells coordinate across tissues and organs
to determine where each cell divides and differentiates. This coordination requires complex …

Decoding how tissue properties emerge across multiple spatial and temporal scales from
the integration of local signals is a grand challenge in quantitative biology. For example, the …

The robust specification of organ development depends on coordinated cell-cell
communication. This process requires signal integration among multiple pathways, relying …

Skin homeostasis is maintained by stem cells, which must communicate to balance their
regenerative behaviors. Yet, how adult stem cells signal across regenerative tissue remains …

Simple Summary Eyespot foci on butterfly wings function as organizers for eyespot color
patterns during development. Here, we microscopically examined the scales, sockets, and …

Background One hypothesis surrounding the origin of novel traits is that they originate from
the co-option of pre-existing genes or larger gene regulatory networks into novel …

Information flow within and between cells depends significantly on calcium (Ca2+) signaling
dynamics. However, the biophysical mechanisms that govern emergent patterns of Ca2+ …

Corals build their skeletons using extracellular calcifying fluid located in the tissue–skeleton
interface. However, the mechanism by which corals control the transport of calcium and …

Highlights•Eyespots are diversified color pattern elements found on Nymphalid butterfly
wings.•Eyespot diversification is shaped by natural and sexual selection.•Eyespots develop …

With the exception of a few moth and butterfly species, gene-editing tools in Lepidoptera
have been lagging behind other well-studied insects. In order to elucidate gene function …