Data-independent acquisition mass spectrometry (DIA-MS) is a next generation proteomic
methodology that generates permanent digital proteome maps offering highly reproducible …

The data‐independent acquisition mass spectrometry (DIA‐MS) has rapidly evolved as a
powerful alternative for highly reproducible proteome profiling with a unique strength of …

Genomics-based neoantigen discovery can be enhanced by proteomic evidence, but there
remains a lack of consensus on the performance of different quality control methods for …

Abstract Data-Independent Acquisition (DIA) is a method to improve consistent identification
and precise quantitation of peptides and proteins by mass spectrometry (MS). The targeted …

Host cell proteins (HCPs) are process-related impurities derived from the manufacturing of
recombinant biotherapeutics. Residual HCP in drug products, ranging from 1 to 100 ppm (ng …

Neurons are highly compartmentalized cells with tightly controlled subcellular protein
organization. While brain transcriptome, connectome and global proteome maps are being …

Most catalytic, structural and regulatory functions of the cell are carried out by functional
modules, typically complexes containing or consisting of proteins. The composition and …

Background Plasmodium falciparum causes the majority of malaria mortality worldwide, and
the disease occurs during the asexual red blood cell (RBC) stage of infection. In the …

Thyroid nodules occur in about 60% of the population. A major challenge in thyroid nodule
diagnosis is to distinguish between follicular adenoma (FA) and carcinoma (FTC). Here, we …

Efficient peptide and protein identifications from data-independent acquisition mass
spectrometric (DIA-MS) data typically rely on a project-specific spectral library with a suitable …