Biomedical applications of calixarenes: state of the art and perspectives
YC Pan, XY Hu, DS Guo - Angewandte Chemie International …, 2021 - Wiley Online Library
Calixarenes (CAs), representing the third generation of supramolecular hosts and one of the
most widely studied macrocyclic scaffolds, offer (almost) unlimited structure and application …
most widely studied macrocyclic scaffolds, offer (almost) unlimited structure and application …
Recent updates on development of protein-tyrosine phosphatase 1B inhibitors for treatment of diabetes, obesity and related disorders
S Singh, AS Grewal, R Grover, N Sharma, B Chopra… - Bioorganic …, 2022 - Elsevier
The aim of this review was to discuss an overview of type 2 diabetes; biology of PTP1B; role
of PTP1B in metabolic disorders; and recent updates in the development of PTP1B inhibitors …
of PTP1B in metabolic disorders; and recent updates in the development of PTP1B inhibitors …
Applications of calixarenes in cancer chemotherapy: facts and perspectives
Research on the therapeutic applications of calixarene derivatives is an emerging area of
interest. The anticancer activity of various functionalized calixarenes has been reported by …
interest. The anticancer activity of various functionalized calixarenes has been reported by …
Functionalized calix [4] arenes as potential therapeutic agents
Calixarenes, composed of phenolic units linked by methylene bridges at the 2, 6‐positions,
represent a versatile class of macrocyclic compounds in supramolecular chemistry that can …
represent a versatile class of macrocyclic compounds in supramolecular chemistry that can …
Host-Guest Complexation of Oxaliplatin and Para-Sulfonatocalix[n]Arenes for Potential Use in Cancer Therapy
P-sulfonatocalix [n] arenes have demonstrated a great potential for encapsulation of
therapeutic drugs via host-guest complexation to improve solubility, stability, and …
therapeutic drugs via host-guest complexation to improve solubility, stability, and …
Anionic amphiphilic calixarenes for peptide assembly and delivery
Shape-persistent macrocycles enable superior control on molecular self-assembly, allowing
the preparation of well-defined nanostructures with new functions. Here, we report on …
the preparation of well-defined nanostructures with new functions. Here, we report on …
Investigation of the host-guest complexation between 4-sulfocalix [4] arene and nedaplatin for potential use in drug delivery
Macromolecules including macrocyclic species have been reported to have the potential to
encapsulate biologically active compounds such as drugs through host-guest complexation …
encapsulate biologically active compounds such as drugs through host-guest complexation …
Calixarene-based pure and mixed assemblies for biomedical applications
Y Razuvayeva, R Kashapov… - Supramolecular …, 2020 - Taylor & Francis
The spontaneous preparation of well-defined functional nanoscale systems is very
important, since this formulation process requires additional resources, external supply of …
important, since this formulation process requires additional resources, external supply of …
The design strategy of selective PTP1B inhibitors over TCPTP
XQ Li, LJ Wang, DY Shi - Bioorganic & medicinal chemistry, 2016 - Elsevier
Protein tyrosine phosphatase 1B (PTP1B) has already been well studied as a highly
validated therapeutic target for diabetes and obesity. However, the lack of selectivity limited …
validated therapeutic target for diabetes and obesity. However, the lack of selectivity limited …
Calixarene-based phosphinic acids as inhibitors of protein tyrosine phosphatases
VM Buldenko, VV Trush, OL Kobzar… - Bioorganic & medicinal …, 2019 - Elsevier
In the present work, the derivatives of calix [4] arene, thiacalix [4] arene, and sulfonylcalix [4]
arene bearing four methylene (phenyl) phosphinic acid groups on the upper rim of the …
arene bearing four methylene (phenyl) phosphinic acid groups on the upper rim of the …