Aldosterone, a vital hormone of the human body, has various pathophysiological roles. The
excess of aldosterone, also known as primary aldosteronism, is the most common …

Aldosterone's role in the kidney and its pathophysiologic actions in hypertension are well
known. However, its role or that of its receptor [minieralocorticoid receptor (MR)] in other …

This comprehensive review offers a thorough exploration of recent advancements in our
understanding of the intricate cardiovascular complications associated with Primary …

BACKGROUND: Salt sensitivity of blood pressure (SSBP) is a substantial risk factor for
cardiovascular morbidity and mortality. Striatin (STRN) is critical for estrogen and …

Excess aldosterone production has been the focus of what was thought to be a relatively
uncommon condition; we now know that was an incorrect assumption. 1 Additionally, it is …

Hypertension is one of the leading causes of death worldwide and the primary risk factor for
ischemic and hemorrhagic strokes and coronary artery disease. The role of aldosterone and …

Intravital microscopy is a powerful tool to study thrombosis in real time. The kinetics of
thrombus formation and progression in vivo is studied after inflicting damage to the …

Abstract Increased endothelin‐1 (ET‐1) levels in patients with sickle cell disease (SCD) and
transgenic mouse models of SCD contribute to disordered hematological, vascular, and …

• A promising approach to overcome these difficulties is genetics. Using data from human
genetic and genetically modified animal studies has identified potential mechanisms linking …