[HTML][HTML] A narrative review of central nervous system involvement in acute leukemias

D Deak, N Gorcea-Andronic, V Sas… - Annals of …, 2021 - ncbi.nlm.nih.gov
Acute leukemias (both myeloid and lymphoblastic) are a group of diseases for which each
year more successful therapies are implemented. However, in a subset of cases the overall …

Morphological and immunophenotypic clues to the WHO categories of acute myeloid leukaemia

BJ Bain, MC Béné - Acta haematologica, 2019 - karger.com
Diagnosis and classification of acute myeloid leukaemia (AML) require cytogenetic and
molecular genetic investigation. However, while these evaluations are pending, morphology …

Prognostic factors for acute myeloid leukaemia in adults–biological significance and clinical use

R Liersch, C Müller‐Tidow, WE Berdel… - British journal of …, 2014 - Wiley Online Library
Acute myeloid leukaemia (AML) is a heterogenous disease. Prognosis of AML is influenced
both by patient‐specific as well as disease‐specific factors. Age is the most prominent …

Mixed-phenotype acute leukemia: diagnostic criteria and pitfalls

NJ Charles, DF Boyer - Archives of pathology & laboratory …, 2017 - meridian.allenpress.com
Mixed-phenotype acute leukemia (MPAL) is a heterogeneous category in the World Health
Organization classification that comprises acute leukemias with discrete admixed …

Antibody therapies for acute myeloid leukemia: unconjugated, toxin-conjugated, radio-conjugated and multivalent formats

BA Williams, A Law, J Hunyadkurti, S Desilets… - Journal of clinical …, 2019 - mdpi.com
In recent decades, therapy for acute myeloid leukemia (AML) has remained relatively
unchanged, with chemotherapy regimens primarily consisting of an induction regimen …

Introduction to the diagnosis and classification of monocytic‐lineage leukemias by flow cytometry

S Matarraz, J Almeida, J Flores‐Montero… - Cytometry Part B …, 2017 - Wiley Online Library
Despite diagnostic criteria are currently available for the distinct subtypes of monocytic‐
lineage neoplasias, a number of partially overlapping features still remain evident, which …

Endothelial cells: major players in acute myeloid leukaemia

S Fodil, M Arnaud, C Vaganay, A Puissant, E Lengline… - Blood Reviews, 2022 - Elsevier
The role of the vascular microenvironment is increasingly studied in acute myeloid
leukaemia (AML). Complex interactions between endothelial cells (ECs) and pre-leukaemic …

Flow cytometric identification of hematopoietic and leukemic blast cells for tailored clinical follow-up of acute myeloid leukemia

V Weeda, SGC Mestrum, MPG Leers - International journal of molecular …, 2022 - mdpi.com
Acute myeloid leukemia (AML) is a myeloid malignancy that is characterized by the
accumulation of leukemic blast cells, which originate from hematopoietic stem cells that …

[HTML][HTML] Aberrant phenotypes in acute myeloid leukemia and its relationship with prognosis and survival: a systematic review and meta-analysis

LHS Pinheiro, LD Trindade… - … journal of hematology …, 2020 - ncbi.nlm.nih.gov
Background: The aim of this review was to evaluate the influence of aberrant phenotypes in
prognosis and survival in acute myeloid leukemia (AML) patients by multiparametric flow …

High IL2RA mRNA expression is an independent adverse prognostic biomarker in core binding factor and intermediate-risk acute myeloid leukemia

W Du, J He, W Zhou, S Shu, J Li, W Liu, Y Deng… - Journal of translational …, 2019 - Springer
Background Elevated protein expressions of CD markers such as IL2RA/CD25,
CXCR4/CD184, CD34 and CD56 are associated with adverse prognosis in acute myeloid …