Background Vasopressors are administered to critically ill patients with vasodilatory shock
not responsive to volume resuscitation, and less often in cardiogenic shock, and …

Septic shock remains a health care concern associated with significant morbidity and
mortality. The Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic …

Early initiation of a multimodal treatment strategy in the management of vasopressors during
septic shock has been advocated to reduce delays in restoring adequate organ perfusion …

Objectives: The objectives of this study were to: 1) determine the association between
vasopressor dosing intensity during the first 6 hours and first 24 hours after the onset of …

Background vasopressin is commonly used as a second-line vasopressor for patients with
septic shock, but the optimal timing of initiation is uncertain. This study was designed to …

Background: Septic shock is a distributive shock with decreased systemic vascular
resistance and MAP. Septic shock contributes to the most common causes of death in the …

Background The effect of early vasopressin initiation on clinical outcomes in patients with
septic shock is uncertain. A systematic review and meta-analysis was performed to evaluate …

This review of the use of vasopressin aims to be comprehensive and highly practical, based
on the available scientific evidence and our extensive clinical experience with the drug. It …

Background Septic shock is a leading cause of death in intensive care units (ICUs), with
short-term mortality rates of 35–40%. Vasopressin (AVP) is a second-line vasoactive agent …

Background Norepinephrine (NE) has currently been the first-choice vasopressor in treating
septic shock despite generally insufficient for patients with refractory septic shock. The aim of …