[HTML][HTML] Harnessing the Systemic Biology of Functional Decline and Cachexia to Inform more Holistic Therapies for Incurable Cancers

A Willbanks, M Seals, R Karmali, I Roy - Cancers, 2024 - mdpi.com
Simple Summary Approaches to treat advanced cancer within tumor biology have been
largely unsuccessful. This review investigates the biology downstream of the tumor as a …

Prevalence and prognosis of cachexia according to the Asian Working Group for Cachexia criteria in sarcopenic dysphagia: A retrospective cohort study

H Wakabayashi, S Kakehi, S Mizuno, T Kinoshita… - Nutrition, 2024 - Elsevier
Objective The aim is to examine the prevalence and prognosis of cachexia according to the
Asian Working Group for Cachexia (AWGC) criteria in patients with sarcopenic dysphagia …

Decreased bed mobility function is associated with post-discharge mortality for cancer patients in inpatient rehabilitation

I Roy, J Marks, J Fram, P Jayabalan… - American Journal of …, 2024 - journals.lww.com
Objective The establishment of rehabilitation goals for hospitalized cancer patients depends
on accurate medical prognosis and matching goals to clinical timelines. Current tools for …

Muscle wasting and frailty in head and neck cancer

EW Villanueva, R Kelly, L Henderson, I Roy - Head and Neck Cancer …, 2025 - Elsevier
Muscle wasting disorders play a major role in the quality of life (QoL), function, and disease
progression of individuals with head and neck cancer (HNC). Cachexia is perhaps the word …

[PDF][PDF] Survey of Awareness of Terminology Related to Functional Impairment and Muscle Health Among Rehabilitation Healthcare Staff

K Hori, Y Yoshimura - Annals of Geriatric Medicine and Research, 2024 - e-agmr.org
Older adults undergoing rehabilitation are often complicated by functional and nutritional
impairments. 1-3) Research has highlighted the importance of nutritional rehabilitation in …

Gait speed is a biomarker of cancer-associated cachexia decline and recovery

I Roy, B Binder-Markey, D Sychowski, A Willbanks… - bioRxiv, 2023 - biorxiv.org
Background: Progressive functional decline is a key element of cancer-associated cachexia.
No therapies have successfully translated to the clinic due to an inability to measure and …