Scleritis is a sight-threatening inflammation characterized by severe pain and redness of the
eye. It can cause blindness by severe complications like scleral and corneal necrosis …

Whether tumor necrosis factor alpha (TNF‐α) gene polymorphisms (SNPs) influence
disease susceptibility and treatment of patients with juvenile idiopathic arthritis (JIA) is …

Objective JIA is an autoimmune, inflammatory disease with involvement of innate and
adaptive immune responses. However, the role of neutrophils in JIA pathogenesis remains …

The treatment of juvenile idiopathic arthritis (JIA) has substantially evolved over the past two
decades. Research has been conducted and is ongoing on how therapies can best be …

It has been estimated that autoimmune diseases (AIDs) affect 5-8% of the US population.
AIDs are a serious public health problem worldwide. These diseases are chronic conditions …

Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic condition in
childhood, with many children requiring immunomodulatory therapies for many years …

The pathogenesis of cigarette-smoke-exposure-induced pulmonary vasculature impairment
is unclear. Cigarette-smoke-exposure-induced the accumulation of tumour necrosis factor …

Objective To investigate the genetic contribution of TNF-α gene polymorphisms on the
disease course and therapeutic response in patients with juvenile idiopathic arthritis (JIA) …

Vitamin D receptor (VDR) gene FokI (rs2228570) polymorphism was postulated to influence
outcome of several inflammatory diseases. The aim of this study was to evaluate the …

HTLV-1-infected individuals may develop a neurologic inflammatory condition known as
HTLV-1-associated myelopathy (HAM/TSP), in which the high production of TNF is …