Synthesis, biological evaluation, and docking studies of 3-(substituted)-aryl-5-(9-methyl-3-carbazole)-1H-2-pyrazolines as potent anti-inflammatory and antioxidant …

BP Bandgar, LK Adsul, HV Chavan, SS Jalde… - Bioorganic & medicinal …, 2012 - Elsevier
A novel series of 3-(substituted)-aryl-5-(9-methyl-3-carbazole)-1H-2-pyrazolines (5a–o) has
been synthesized and the structures of newly synthesized compounds were characterized …

Valorization of onion solid waste and their flavonols for assessment of cytotoxicity, enzyme inhibitory and antioxidant activities

A Nile, SH Nile, DH Kim, YS Keum, PG Seok… - Food and Chemical …, 2018 - Elsevier
Onion (Allium cepa L.) is rich with flavonols which perceived benefits to human health.
Flavonols like quercetin and quercetin glycosides from onion solid waste (OSW) have been …

Synthesis of extended conjugated indolyl chalcones as potent anti-breast cancer, anti-inflammatory and antioxidant agents

PS Bhale, HV Chavan, SB Dongare… - Bioorganic & medicinal …, 2017 - Elsevier
In the present investigation, synthesis of a series of extended conjugated δ-chloro-α-cyano
substituted indolyl chalcones (5a–p) was accomplished by reacting 3-cyanoacetylindole 2 …

Inhibition properties of propolis extracts to some clinically important enzymes

N Baltas, O Yildiz, S Kolayli - Journal of Enzyme Inhibition and …, 2016 - Taylor & Francis
The present study was conducted to envisage inhibition effects of propolis on the crucial
enzymes, urease, xanthine oxidase (XO) and acetylcholinesterase (AChE). Some of the …

Honey as an apitherapic product: its inhibitory effect on urease and xanthine oxidase

H Sahin - Journal of enzyme inhibition and medicinal chemistry, 2016 - Taylor & Francis
The aim of this study was to evaluate new natural inhibitor sources for the enzymes urease
and xanthine oxidase (XO). Chestnut, oak and polyfloral honey extracts were used to …

Heterocyclic curcumin derivatives of pharmacological interest: Recent progress

M Martinez-Cifuentes, B Weiss-Lopez… - Current Topics in …, 2015 - ingentaconnect.com
Curcumin, a natural yellow polyphenol, is isolated from the herb Curcuma longa L.(turmeric),
a member of the ginger family. It has been extensively studied due to their multiple …

Synthesis and pharmacological evaluation of combretastatin-A4 analogs of pyrazoline and pyridine derivatives as anticancer, anti-inflammatory and antioxidant …

SN Shringare, HV Chavan, PS Bhale… - Medicinal Chemistry …, 2018 - Springer
Three category of N 1-phenyl pyrazoline (5a–e), N 1-phenyl-sulfonyl pyrazoline (6a–e), and
pyridine analogs (8a–d) of combretastatin-A4 were synthesized. The structures of …

Synthesis and pharmacological evaluation of pyrazoline and pyrimidine analogs of combretastatin-A4 as anticancer, anti-inflammatory and antioxidant agents

SN Shringare, HV Chavan, PS Bhale… - Croatica Chemica …, 2018 - hrcak.srce.hr
Sažetak A library of 3, 5-diaryl-1-carbothioamide-pyrazoline (5a–j), N1-phenyl sulfonyl
pyrazoline (6a–e) and pyrimidine (7a) analogs of combretastatin-A4 were synthesized and …

PEG Mediated Synthesis and Biological Evaluation of Asymmetrical Pyrazole Curcumin Analogues as Potential Analgesic, Anti‐Inflammatory and Antioxidant Agents

SY Jadhav, RB Bhosale, SP Shirame… - Chemical Biology & …, 2015 - Wiley Online Library
The new series of asymmetrical pyrazole curcumin analogues 4a–g were synthesized by
using polyethylene glycol (PEG‐400) as a green reaction medium and evaluated for their in …

Synthesis and biological evaluation of novel series of aminopyrimidine derivatives as urease inhibitors and antimicrobial agents

LK Adsul, BP Bandgar, HV Chavan… - Journal of enzyme …, 2013 - Taylor & Francis
A novel series of carbazole substituted aminopyrimidines (5a-p) were synthesized and
screened for their in vitro urease inhibition and antimicrobial activity. Among the compounds …