Metabolic syndrome-related kidney injury: a review and update

L Lin, W Tan, X Pan, E Tian, Z Wu… - Frontiers in endocrinology, 2022 - frontiersin.org
Metabolic syndrome (MetS) includes visceral obesity, hyperglycemia, dyslipidemia, and
hypertension. The prevalence of MetS is 20-25%, which is an important risk factor for chronic …

Exploring the nexus: The place of kidney diseases within the cardiovascular-kidney-metabolic syndrome spectrum

M Kanbay, M Guldan, L Ozbek, S Copur… - European journal of …, 2024 - Elsevier
Abstract Cardiovascular-kidney-metabolic (CKM) syndrome and chronic kidney disease
(CKD) are two significant comorbidities affecting a large proportion of the general population …

Long-term intermittent fasting improves neurological function by promoting angiogenesis after cerebral ischemia via growth differentiation factor 11 signaling activation

Z Liu, M Liu, G Jia, J Li, L Niu, H Zhang, Y Qi, H Sun… - PLoS …, 2023 - journals.plos.org
Intermittent fasting (IF), an alternative to caloric restriction, is a form of time restricted eating.
IF conditioning has been suggested to have neuroprotective effects and potential long-term …

MeCP2 regulates Gdf11, a dosage-sensitive gene critical for neurological function

SS Bajikar, AG Anderson, J Zhou, MA Durham… - Elife, 2023 - elifesciences.org
Loss-and gain-of-function of MeCP2 causes Rett syndrome (RTT) and MECP2 duplication
syndrome (MDS), respectively. MeCP2 binds methyl-cytosines to finely tune gene …

Progress in the relationship between GDF11 and depression

X Jin, W Guan - Life Sciences, 2024 - Elsevier
Annually, the frequency of morbidity in depression has increased progressively in response
to life stressors, and there is an increasing trend toward younger morbidity. The …

GDF11: An emerging therapeutic target for liver diseases and fibrosis

P Habibi, K Falamarzi, ND Ebrahimi… - Journal of Cellular …, 2024 - Wiley Online Library
Abstract Growth differentiation factor 11 (GDF11), also known as bone morphogenetic
protein 11 (BMP11), has been identified as a key player in various biological processes …

The correlation between circulating growth differentiation factor 11 and the risk of osteopenia/osteoporosis in men

M Jin, R Cao, X Niu, P Shan - Archives of Osteoporosis, 2023 - Springer
Our results suggest that the serum GDF11 concentration is significantly associated with the
risk of bone metabolism dysfunction in men and may be a useful target for prediction of …

Growth Differentiation Factor 11: Genetic Regulation and Implications in Human Disease

A Starcher - 2021 - search.proquest.com
Abstract Growth Differentiation Factor 11 (GDF11) serves vital roles in the developing
embryo, governing organogenesis and axial patterning, yet surprisingly little is known about …