Fibroblast growth factors (FGFs) act as key signalling molecules in brain development,
maintenance, and repair. They influence the intricate relationship between myelinating cells …

FGFR (fibroblast growth factor receptor) signaling controls fundamental processes in
embryonic, fetal and adult human life. The magnitude, duration, and location of FGFR …

Following spinal cord injury (SCI), a multitude of intrinsic and extrinsic factors adversely
affect the gene programs that govern the expression of regeneration-associated genes …

Axonal growth during normal development and axonal regeneration rely on the action of
many receptor signaling systems and complexes, most of them located in specialized raft …

Recent findings have drawn attention to the role of membrane traffic in the signaling of
vascular endothelial growth factor (VEGF). The significance of this development stems from …

The fibroblast growth factor (FGF) family regulates various and important aspects of nervous
system development, ranging from the well-established roles in neuronal patterning to more …

Fibroblast growth factor 2 (FGF2) induces endothelial cell migration and angiogenesis
through two classes of receptors: receptor tyrosine kinases, such as FGF receptor 1 …

Axon branching is a critical process ensuring a high degree of interconnectivity for neural
network formation. As branching occurs at sites distant from the soma, it is necessary that …

Angiogenesis contributes to the development of numerous disorders. Even though fibroblast
growth factors (FGFs) were discovered as mediators of angiogenesis more than 30 years …

During development, neurons progress through rapid yet stereotypical shape changes to
achieve proper neuronal connectivity. This morphological progression requires carefully …