[HTML][HTML] Circulating tumor cell isolation for cancer diagnosis and prognosis

Z Deng, S Wu, Y Wang, D Shi - EBioMedicine, 2022 - thelancet.com
Circulating tumor cells (CTCs) are tumor cells that shed from the primary tumor and
intravasate into the peripheral blood circulation system responsible for metastasis. Sensitive …

Unravelling tumour heterogeneity by single-cell profiling of circulating tumour cells

L Keller, K Pantel - Nature Reviews Cancer, 2019 - nature.com
Single-cell technologies have contributed to unravelling tumour heterogeneity, now
considered a hallmark of cancer and one of the main causes of tumour resistance to cancer …

[HTML][HTML] Potential clinical utility of liquid biopsies in ovarian cancer

JW Zhu, P Charkhchi, MR Akbari - Molecular cancer, 2022 - Springer
Background Ovarian cancer (OC) is the most lethal gynecologic malignancy worldwide. One
of the main challenges in the management of OC is the late clinical presentation of disease …

[HTML][HTML] A review of circulating tumour cell enrichment technologies

AJ Rushton, G Nteliopoulos, JA Shaw, RC Coombes - Cancers, 2021 - mdpi.com
Simple Summary Circulating tumour cells (CTCs) are cancer cells shed into the bloodstream
from tumours and their analysis can provide important insights into cancer detection and …

[HTML][HTML] Tracking cancer progression: From circulating tumor cells to metastasis

F Castro-Giner, N Aceto - Genome medicine, 2020 - Springer
The analysis of circulating tumor cells (CTCs) is an outstanding tool to provide insights into
the biology of metastatic cancers, to monitor disease progression and with potential for use …

Fusobacterium nucleatum and cancer

T Alon‐Maimon, O Mandelboim… - Periodontology …, 2022 - Wiley Online Library
Accumulating evidence demonstrates that the oral pathobiont Fusobacterium nucleatum is
involved in the progression of an increasing number of tumors types. Thus far, the …

[HTML][HTML] Biology and clinical relevance of EpCAM

L Keller, S Werner, K Pantel - Cell stress, 2019 - ncbi.nlm.nih.gov
Epithelial cell adhesion molecule (EpCAM) is a transmembrane glycoprotein primarily
known to mediate homotypic cell contacts in epithelia tissues. Because EpCAM expression …

[HTML][HTML] Epithelial cell adhesion molecule: an anchor to isolate clinically relevant circulating tumor cells

In the last few decades, the epithelial cell adhesion molecule (EpCAM) has received
increased attention as the main membrane marker used in many enrichment technologies to …

Epithelial‐to‐mesenchymal‐like transition events in melanoma

D Pedri, P Karras, E Landeloos, JC Marine… - The FEBS …, 2022 - Wiley Online Library
Epithelial‐to‐mesenchymal transition (EMT), a process through which epithelial tumor cells
acquire mesenchymal phenotypic properties, contributes to both metastatic dissemination …

[HTML][HTML] The role of proteoglycans in cancer metastasis and circulating tumor cell analysis

TD Ahrens, SR Bang-Christensen… - Frontiers in cell and …, 2020 - frontiersin.org
Circulating tumor cells (CTCs) are accessible by liquid biopsies via an easy blood draw.
They represent not only the primary tumor site, but also potential metastatic lesions, and …