Metabotropic glutamate (mGlu) receptors were discovered in the mid 1980s and originally
described as glutamate receptors coupled to polyphosphoinositide hydrolysis. Almost 6500 …

Amphetamines represent a class of psychotropic compounds, widely abused for their
stimulant, euphoric, anorectic, and, in some cases, emphathogenic, entactogenic, and …

Amphetamine-related drugs, such as 3, 4-methylenedioxymethamphetamine (MDMA) and
methamphetamine (METH), are popular recreational psychostimulants. Several preclinical …

Methamphetamine (METH) is an illicit psychostimulant that is widely abused in the world.
Several lines of evidence suggest that chronic METH abuse leads to neurodegenerative …

Methamphetamine (METH) is a highly addictive psychostimulant and one of the most widely
abused drugs worldwide. The continuous use of METH eventually leads to drug addiction …

Synchrotron-based x-ray fluorescence microscopy, immunofluorescence, and Western
blotting were used to investigate changes in copper (Cu) and Cu-associated pathways in the …

Adaptation of the nervous system to different chemical and physiologic conditions is
important for the homeostasis of brain processes and for learning and remembering …

The drugs of abuse, methamphetamine and MDMA, produce long‐term decreases in
markers of biogenic amine neurotransmission. These decreases have been traditionally …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor symptoms
including tremor and bradykinesia. The primary pathophysiology underlying PD is the …

In recent years there have been tremendous advances in our understanding of the circuitry
of the basal ganglia and our ability to predict the behavioural effects of specific cellular …