Radiation damage to biological macromolecules∗
In this review, we describe recent research developments into radiation damage effects in
macromolecular X-ray crystallography observed at synchrotrons and X-ray free electron …
macromolecular X-ray crystallography observed at synchrotrons and X-ray free electron …
The red edge: bilin-binding photoreceptors as optogenetic tools and fluorescence reporters
This review adds the bilin-binding phytochromes to the Chemical Reviews thematic issue
“Optogenetics and Photopharmacology”. The work is structured into two parts. We first …
“Optogenetics and Photopharmacology”. The work is structured into two parts. We first …
Plant phytochrome B is an asymmetric dimer with unique signalling potential
Many aspects of plant photoperception are mediated by the phytochrome (Phy) family of
bilin-containing photoreceptors that reversibly interconvert between inactive Pr and active …
bilin-containing photoreceptors that reversibly interconvert between inactive Pr and active …
An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography
Serial femtosecond crystallography has opened up many new opportunities in structural
biology. In recent years, several approaches employing light-inducible systems have …
biology. In recent years, several approaches employing light-inducible systems have …
A guide to time‐resolved structural analysis of light‐activated proteins
Dynamical changes in protein structures are essential for protein function and occur over
femtoseconds to seconds timescales. X‐ray free electron lasers have facilitated …
femtoseconds to seconds timescales. X‐ray free electron lasers have facilitated …
Tips and turns of bacteriophytochrome photoactivation
H Takala, P Edlund, JA Ihalainen… - Photochemical & …, 2020 - pubs.rsc.org
Phytochromes are ubiquitous photosensor proteins, which control the growth, reproduction
and movement in plants, fungi and bacteria. Phytochromes switch between two …
and movement in plants, fungi and bacteria. Phytochromes switch between two …
Bistable photoswitch allows in vivo control of hematopoiesis
L Albert, J Nagpal, W Steinchen, L Zhang… - ACS central …, 2021 - ACS Publications
Optical control has enabled functional modulation in cell culture with unparalleled
spatiotemporal resolution. However, current tools for in vivo manipulation are scarce. Here …
spatiotemporal resolution. However, current tools for in vivo manipulation are scarce. Here …
The structure of Arabidopsis phytochrome A reveals topological and functional diversification among the plant photoreceptor isoforms
ES Burgie, H Li, ZTK Gannam, KE McLoughlin… - Nature plants, 2023 - nature.com
Plants employ a divergent cohort of phytochrome (Phy) photoreceptors to govern many
aspects of morphogenesis through reversible photointerconversion between inactive Pr and …
aspects of morphogenesis through reversible photointerconversion between inactive Pr and …
Signaling by a bacterial phytochrome histidine kinase involves a conformational cascade reorganizing the dimeric photoreceptor
ES Burgie, K Basore, MJ Rau, B Summers… - Nature …, 2024 - nature.com
Phytochromes (Phys) are a divergent cohort of bili-proteins that detect light through
reversible interconversion between dark-adapted Pr and photoactivated Pfr states. While our …
reversible interconversion between dark-adapted Pr and photoactivated Pfr states. While our …
Green/red light-sensing mechanism in the chromatic acclimation photosensor
T Nagae, Y Fujita, T Tsuchida, T Kamo, R Seto… - Science …, 2024 - science.org
Certain cyanobacteria alter their photosynthetic light absorption between green and red, a
phenomenon called complementary chromatic acclimation. The acclimation is regulated by …
phenomenon called complementary chromatic acclimation. The acclimation is regulated by …