Changes in the epidemiological landscape of invasive candidiasis

F Lamoth, SR Lockhart, EL Berkow… - Journal of …, 2018 - academic.oup.com
The epidemiology of invasive candidiasis has evolved in recent years, warranting a review
of the changes and the implications for current and future diagnosis and treatment. The …

Candida parapsilosis: from genes to the bedside

R Tóth, J Nosek, HM Mora-Montes… - Clinical microbiology …, 2019 - Am Soc Microbiol
Patients with suppressed immunity are at the highest risk for hospital-acquired infections.
Among these, invasive candidiasis is the most prevalent systemic fungal nosocomial …

High-resolution mycobiota analysis reveals dynamic intestinal translocation preceding invasive candidiasis

B Zhai, M Ola, T Rolling, NL Tosini, S Joshowitz… - Nature medicine, 2020 - nature.com
The intestinal microbiota is a complex community of bacteria, archaea, viruses, protists and
fungi,. Although the composition of bacterial constituents has been linked to immune …

Epidemiology and risk factors for invasive candidiasis

N Yapar - Therapeutics and clinical risk management, 2014 - Taylor & Francis
The number of immunosuppressive patients has increased significantly in recent years.
These patients are at risk for opportunistic infections, especially fungal infections …

Long-term antibiotic exposure promotes mortality after systemic fungal infection by driving lymphocyte dysfunction and systemic escape of commensal bacteria

RA Drummond, JV Desai, EE Ricotta, M Swamydas… - Cell host & …, 2022 - cell.com
Antibiotics are a modifiable iatrogenic risk factor for the most common human nosocomial
fungal infection, invasive candidiasis, yet the underlying mechanisms remain elusive. We …

Epidemiology and Outcomes of Invasive Candidiasis Due to Non-albicans Species of Candida in 2,496 Patients: Data from the Prospective Antifungal Therapy …

MA Pfaller, DR Andes, DJ Diekema, DL Horn… - PloS one, 2014 - journals.plos.org
This analysis describes the epidemiology and outcomes of invasive candidiasis caused by
non-albicans species of Candida in patients enrolled in the Prospective Antifungal Therapy …

Worrisome trends in incidence and mortality of candidemia in intensive care units (Paris area, 2002–2010)

O Lortholary, C Renaudat, K Sitbon, Y Madec… - Intensive care …, 2014 - Springer
Purpose To analyze trends in incidence and mortality of candidemia in intensive care units
(ICUs) vs. non-ICU hospitalized patients and to determine risk factors for infection by specific …

[HTML][HTML] How to interpret MICs of antifungal compounds according to the revised clinical breakpoints v. 10.0 European committee on antimicrobial susceptibility testing …

MC Arendrup, N Friberg, M Mares, G Kahlmeter… - Clinical Microbiology …, 2020 - Elsevier
Background EUCAST has revised the definition of the susceptibility category I from
'Intermediate'to 'Susceptible, Increased exposure'. This implies that I can be used where the …

Epidemiology and outcomes of candidemia in 3648 patients: data from the Prospective Antifungal Therapy (PATH Alliance®) registry, 2004–2008

M Pfaller, D Neofytos, D Diekema, N Azie… - … and infectious disease, 2012 - Elsevier
This analysis describes the epidemiology and outcomes of candidemia in patients enrolled
in the Prospective Antifungal Therapy Alliance (PATH Alliance®) registry from 2004 to 2008 …

Echinocandin resistance: an emerging clinical problem?

MC Arendrup, DS Perlin - Current opinion in infectious diseases, 2014 - journals.lww.com
Echinocandin resistance is increasingly encountered and its occurrence makes
susceptibility testing essential, particularly in patients with prior exposure. The further …