Radiometals possess an exceptional breadth of decay properties and have been applied to
medicine with great success for several decades. The majority of current clinical use …

Radiometals comprise many useful radioactive isotopes of various metallic elements. When
properly harnessed, these have valuable emission properties that can be used for …

The International Commission on Radiation Units and Measurements (ICRU), since its
inception in 1925, has had as its principal objective the development of internationally …

Purpose The objective of this study was to investigate and present the early results on the
efficacy, safety, and quality of life of 225 Ac-DOTATATE targeted alpha therapy (TAT) in …

This review presents an overview of the successes and challenges currently faced in alpha
radionuclide therapy. Alpha particles have an advantage in killing tumour cells as compared …

Alpha-emitters are radionuclides that decay through the emission of high linear energy
transfer α-particles and possess favorable pharmacologic profiles for cancer treatment …

The α-emitting radionuclide actinium-225 possesses nuclear properties that are highly
promising for use in targeted α therapy (TAT), a therapeutic strategy that employs α particle …

The effectiveness of targeted α-therapy (TAT) can be explained by the properties of α-
particles. Alpha particles are helium nuclei and are~ 8,000 times larger than β−-particles …

Radioimmunotherapy (RIT) aims to selectively deliver radionuclides emitting α-particles, β-
particles or Auger electrons to tumors by conjugation to monoclonal antibodies (mAbs) that …

Recent clinical results have demonstrated remarkable treatment responses of late-stage
cancer patients when treated with alpha-emitting radionuclides such as actinium-225 …