Cardiomyocyte regeneration: a consensus statement
Circulation. 2017; 136: 680–686. DOI: 10.1161/CIRCULATIONAHA. 117.029343 August 15,
2017 681 proliferation. 5 It remains unclear whether this regenerative window exists in large …
2017 681 proliferation. 5 It remains unclear whether this regenerative window exists in large …
A brief review of current maturation methods for human induced pluripotent stem cells-derived cardiomyocytes
RE Ahmed, T Anzai, N Chanthra… - Frontiers in cell and …, 2020 - frontiersin.org
Cardiovascular diseases are the leading cause of death worldwide. Therefore, the discovery
of induced pluripotent stem cells (iPSCs) and the subsequent generation of human induced …
of induced pluripotent stem cells (iPSCs) and the subsequent generation of human induced …
Self-assembling human heart organoids for the modeling of cardiac development and congenital heart disease
Congenital heart defects constitute the most common human birth defect, however
understanding of how these disorders originate is limited by our ability to model the human …
understanding of how these disorders originate is limited by our ability to model the human …
Defined engineered human myocardium with advanced maturation for applications in heart failure modeling and repair
Background: Advancing structural and functional maturation of stem cell–derived
cardiomyocytes remains a key challenge for applications in disease modeling, drug …
cardiomyocytes remains a key challenge for applications in disease modeling, drug …
Human pluripotent stem cell-derived atrial and ventricular cardiomyocytes develop from distinct mesoderm populations
The ability to direct the differentiation of human pluripotent stem cells (hPSCs) to the different
cardiomyocyte subtypes is a prerequisite for modeling specific forms of cardiovascular …
cardiomyocyte subtypes is a prerequisite for modeling specific forms of cardiovascular …
Chemically defined generation of human cardiomyocytes
Existing methods for human induced pluripotent stem cell (hiPSC) cardiac differentiation are
efficient but require complex, undefined medium constituents that hinder further elucidation …
efficient but require complex, undefined medium constituents that hinder further elucidation …
Engineering adolescence: maturation of human pluripotent stem cell–derived cardiomyocytes
X Yang, L Pabon, CE Murry - Circulation research, 2014 - Am Heart Assoc
The discovery of human pluripotent stem cells (hPSCs), including both human embryonic
stem cells and human-induced pluripotent stem cells, has opened up novel paths for a wide …
stem cells and human-induced pluripotent stem cells, has opened up novel paths for a wide …
Human induced pluripotent stem cell–derived cardiomyocytes: insights into molecular, cellular, and functional phenotypes
Disease models are essential for understanding cardiovascular disease pathogenesis and
developing new therapeutics. The human induced pluripotent stem cell (iPSC) technology …
developing new therapeutics. The human induced pluripotent stem cell (iPSC) technology …
Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells
Summary Recapitulating three-dimensional (3D) structures of complex organs, such as the
kidney, from pluripotent stem cells (PSCs) is a major challenge. Here, we define the …
kidney, from pluripotent stem cells (PSCs) is a major challenge. Here, we define the …
[HTML][HTML] Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes
Heart disease remains a major cause of death despite advances in medical technology.
Heart-regenerative therapy that uses pluripotent stem cells (PSCs) is a potentially promising …
Heart-regenerative therapy that uses pluripotent stem cells (PSCs) is a potentially promising …