Evolving concepts in progressive supranuclear palsy and other 4-repeat tauopathies
M Stamelou, G Respondek, N Giagkou… - Nature Reviews …, 2021 - nature.com
Tauopathies are classified according to whether tau deposits predominantly contain tau
isoforms with three or four repeats of the microtubule-binding domain. Those in which four …
isoforms with three or four repeats of the microtubule-binding domain. Those in which four …
Clinical spectrum of tauopathies
Tauopathies are both clinical and pathological heterogeneous disorders characterized by
neuronal and/or glial accumulation of misfolded tau protein. It is now well understood that …
neuronal and/or glial accumulation of misfolded tau protein. It is now well understood that …
Tau PET imaging in progressive supranuclear palsy: a systematic review and meta-analysis
J Jin, D Su, J Zhang, X Li, T Feng - Journal of Neurology, 2023 - Springer
Objectives To evaluate the difference of tau burden between patients with progressive
supranuclear palsy (PSP) and healthy controls (HCs) or other neurodegenerative diseases …
supranuclear palsy (PSP) and healthy controls (HCs) or other neurodegenerative diseases …
Magnetic susceptibility in progressive supranuclear palsy variants, Parkinson's disease, and Corticobasal syndrome
R Satoh, SD Weigand, NTT Pham, F Ali… - Movement …, 2023 - Wiley Online Library
Background Previous studies have shown that magnetic susceptibility is increased in
several subcortical regions in progressive supranuclear palsy (PSP). However, it is still …
several subcortical regions in progressive supranuclear palsy (PSP). However, it is still …
Brainstem biomarkers of clinical variant and pathology in progressive supranuclear palsy
RM Grijalva, NTT Pham, Q Huang… - Movement …, 2022 - Wiley Online Library
Background Magnetic resonance brainstem measurements are useful structural biomarkers
in the Richardson's syndrome variant of progressive supranuclear palsy (PSP). However, it …
in the Richardson's syndrome variant of progressive supranuclear palsy (PSP). However, it …
Uncovering spatiotemporal patterns of atrophy in progressive supranuclear palsy using unsupervised machine learning
To better understand the pathological and phenotypic heterogeneity of progressive
supranuclear palsy and the links between the two, we applied a novel unsupervised …
supranuclear palsy and the links between the two, we applied a novel unsupervised …
Differentiating between common PSP phenotypes using structural MRI: a machine learning study
Abstract Background Differentiating Progressive supranuclear palsy-Richardson's syndrome
(PSP-RS) from PSP-Parkinsonism (PSP-P) may be extremely challenging. In this study, we …
(PSP-RS) from PSP-Parkinsonism (PSP-P) may be extremely challenging. In this study, we …
Differential diagnosis of rare subtypes of progressive supranuclear palsy and PSP-like syndromes—infrequent manifestations of the most common form of atypical …
P Krzosek, N Madetko, A Migda, B Migda… - Frontiers in Aging …, 2022 - frontiersin.org
Presently, there is increasing interest in rare PSP (progressive supranuclear palsy) variants,
including PSP-PGF (PSP-progressive gait freezing), PSP-PI (PSP-postural instability), PSP …
including PSP-PGF (PSP-progressive gait freezing), PSP-PI (PSP-postural instability), PSP …
[HTML][HTML] Direct comparison between 18F-Flortaucipir tau PET and quantitative susceptibility mapping in progressive supranuclear palsy
R Satoh, F Ali, H Botha, VJ Lowe, KA Josephs… - Neuroimage, 2024 - Elsevier
Purpose The pattern of flortaucipir tau PET uptake is topographically similar to the pattern of
magnetic susceptibility in progressive supranuclear palsy (PSP); both with increased signal …
magnetic susceptibility in progressive supranuclear palsy (PSP); both with increased signal …
New perspectives in radiological and radiopharmaceutical hybrid imaging in progressive supranuclear palsy: a systematic review
Progressive supranuclear palsy (PSP) is a neurodegenerative disease characterized by four-
repeat tau deposition in various cell types and anatomical regions, and can manifest as …
repeat tau deposition in various cell types and anatomical regions, and can manifest as …