Catalytic oxidation reactions are pivotal transformations in living creatures and chemical
industries, in which metal-oxygen intermediates, including high-valent metal-oxo species …

Conspectus Metalloenzymes, which are proteins containing earth-abundant transition-metal
ions as cofactors in the active site, generate various metal–oxygen intermediates via …

Recently, transition-metal terminal nonoxo complexes have shown a remarkable ability to
activate and functionalize C–H bonds via proton-coupled electron transfer (PCET). Here we …

Introduction of Brønsted acids into biomimetic nonheme reactions promotes the oxidative
ability of metal–oxygen complexes significantly. However, the molecular machinery of the …

The strong C–H bond activation of hydrocarbons is a difficult reaction in environmental and
biological chemistry. Herein, a high-valent manganese (IV)-hydroxo complex,[MnIV (CHDAP …

Arenes are interesting feedstocks for organic synthesis because of their natural abundance.
However, the stability conferred by aromaticity severely limits their reactivity, mostly to …

Binding of Lewis acidic metal ions and Brønsted acid at the metal–oxo group of high-valent
metal–oxo complexes enhances their reactivities significantly in oxidation reactions …

The enzymes manganese lipoxygenase (MnLOX) and manganese superoxide dismutase
(MnSOD) utilize mononuclear Mn centers to effect their catalytic reactions. In the oxidized …

A facile and convenient protocol for the regioselective construction of functionalized 2-
hydroxybenzophenones is described. This protocol involves the Sc (OTf) 3/BF3· OEt2 …

Transition metal–iodosylarene complexes have been proposed to be key intermediates in
the catalytic cycles of metal catalysts with iodosylarene. We report the first X-ray crystal …