Pathophysiology and targeted treatment of cholesterol crystal embolism and the related thrombotic angiopathy

C Shi, E Mammadova‐Bach, C Li… - The FASEB …, 2023 - epub.ub.uni-muenchen.de
Cholesterol crystal (CC) embolism is a complication of advanced atherosclerotic plaques
located in the major arteries. This pathological condition is primarily induced by …

[HTML][HTML] Inhibition of complement factor C5a or C5aR for cholesterol crystal embolism–related vascular thrombosis with microvascular injury and its consequences

D Zhao, C Han, E Mammadova-Bach… - Kidney International, 2024 - Elsevier
Cholesterol crystal embolism (CCE) implies immunothrombosis, tissue necrosis, and organ
failure but no specific treatments are available. As CCE involves complement activation, we …

Looking into the cholesterol crystal ball: is complement the answer?

M Noris, G Remuzzi - Kidney International, 2024 - Elsevier
Cholesterol crystal embolism (CCE) is a complication of atherosclerosis and can cause
microvascular obstruction in multiple organs. Because the consequences may be fatal, and …

[HTML][HTML] Concurrent Cobalamin C and Plasminogen Deficiencies in a Patient with Chronic Thrombotic Microangiopathy

AB Dirim, S Safak, MC Balci, P Ozyavuz, N Garayeva… - Nephron, 2024 - karger.com
Background: Although most patients with atypical hemolytic uremic syndrome (aHUS) have
variants in genes participating in alternative complement pathways, rare variants in non …

Identification of novel prognostic targets in acute kidney injury using bioinformatics and next generation sequencing data analysis

BM Vastrad, CM Vastrad - bioRxiv, 2024 - biorxiv.org
Acute kidney injury (AKI) is a type of renal disease occurs frequently in hospitalized patients,
which may cause abnormal renal function and structure with increase in serum creatinine …