ACP-ADA: a boosting method with data augmentation for improved prediction of anticancer peptides
Cancer is the second-leading cause of death worldwide, and therapeutic peptides that target
and destroy cancer cells have received a great deal of interest in recent years. Traditional …
and destroy cancer cells have received a great deal of interest in recent years. Traditional …
Stacking based ensemble learning framework for identification of nitrotyrosine sites
Protein nitrotyrosine is an essential post-translational modification that results from the
nitration of tyrosine amino acid residues. This modification is known to be associated with …
nitration of tyrosine amino acid residues. This modification is known to be associated with …
iACP-DFSRA: Identification of Anticancer Peptides Based on a Dual-channel Fusion Strategy of ResCNN and Attention
X Wang, Z Zhang, C Liu - Journal of Molecular Biology, 2024 - Elsevier
Anticancer peptides (ACPs) have been widely applied in the treatment of cancer owing to
good safety, rational side effects, and high selectivity. However, the number of ACPs that …
good safety, rational side effects, and high selectivity. However, the number of ACPs that …
Interpretable machine learning of amino acid patterns in proteins: a statistical ensemble approach
Explainable and interpretable unsupervised machine learning helps one to understand the
underlying structure of data. We introduce an ensemble analysis of machine learning …
underlying structure of data. We introduce an ensemble analysis of machine learning …
DL-SPhos: Prediction of serine phosphorylation sites using transformer language model
Serine phosphorylation plays a pivotal role in the pathogenesis of various cellular processes
and diseases. Roughly 81% of human diseases have links to phosphorylation, and an …
and diseases. Roughly 81% of human diseases have links to phosphorylation, and an …
Predicting lysine methylation sites using a convolutional neural network
A Spadaro, A Sharma, I Dehzangi - Methods, 2024 - Elsevier
Protein lysine methylation is a particular type of post translational modification that plays an
important role in both histone and non-histone function regulation in proteins. Deregulation …
important role in both histone and non-histone function regulation in proteins. Deregulation …