Stress physiology of lactic acid bacteria
K Papadimitriou, Á Alegría, PA Bron… - Microbiology and …, 2016 - Am Soc Microbiol
Lactic acid bacteria (LAB) are important starter, commensal, or pathogenic microorganisms.
The stress physiology of LAB has been studied in depth for over 2 decades, fueled mostly by …
The stress physiology of LAB has been studied in depth for over 2 decades, fueled mostly by …
Small regulatory RNAs from low-GC Gram-positive bacteria
S Brantl, R Brückner - RNA biology, 2014 - Taylor & Francis
Small regulatory RNAs (sRNAs) that act by base-pairing were first discovered in so-called
accessory DNA elements—plasmids, phages, and transposons—where they control …
accessory DNA elements—plasmids, phages, and transposons—where they control …
The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems
K Chylinski, A Le Rhun, E Charpentier - RNA biology, 2013 - Taylor & Francis
CRISPR-Cas is a rapidly evolving RNA-mediated adaptive immune system that protects
bacteria and archaea against mobile genetic elements. The system relies on the activity of …
bacteria and archaea against mobile genetic elements. The system relies on the activity of …
Functional genomics using CRISPR-Cas systems, compositions, methods, screens and applications thereof
F Zhang, O Shalem, NE Sanjana, J Doench… - US Patent …, 2020 - Google Patents
The present invention generally relates to libraries, compositions, methods, applications, kits
and screens used in functional genomics that focus on gene function in a cell and that may …
and screens used in functional genomics that focus on gene function in a cell and that may …
Delivery, use and therapeutic applications of the CRISPR-Cas systems and compositions for targeting disorders and diseases using viral components
F Zhang, L Cong, RAN Fei, M Heidenreich… - US Patent …, 2021 - Google Patents
2020-05-07 First worldwide family litigation filed litigation Critical https://patents. darts-ip.
com/? family= 52105124&utm_source= google_patent&utm_medium …
com/? family= 52105124&utm_source= google_patent&utm_medium …
Delivery, engineering and optimization of tandem guide systems, methods and compositions for sequence manipulation
F Zhang, C Lin, RAN Fei - US Patent 11,008,588, 2021 - Google Patents
2016-06-20 Assigned to NATIONAL INSTITUTES OF HEALTH (NIH), US DEPT. OF HEALTH
AND HUMAN SERVICES (DHHS), US GOVERNMENT reassignment NATIONAL …
AND HUMAN SERVICES (DHHS), US GOVERNMENT reassignment NATIONAL …
Compositions and methods of use of CRISPR-Cas systems in nucleotide repeat disorders
B Davidson, C Lin, E Rodriguez, F Zhang - US Patent 10,851,357, 2020 - Google Patents
The invention provides for delivery, engineering and optimization of systems, methods, and
compositions for manipulation of sequences and/or activities of target sequences especially …
compositions for manipulation of sequences and/or activities of target sequences especially …
The Streptococcus suis transcriptional landscape reveals adaptation mechanisms in pig blood and cerebrospinal fluid
Z Wu, C Wu, J Shao, Z Zhu, W Wang, W Zhang, M Tang… - Rna, 2014 - rnajournal.cshlp.org
Streptococcus suis (SS) is an important pathogen of pigs, and it is also recognized as a
zoonotic agent for humans. SS infection may result in septicemia or meningitis in the host …
zoonotic agent for humans. SS infection may result in septicemia or meningitis in the host …
Small RNAs in bacterial virulence and communication
SL Svensson, CM Sharma - Virulence Mechanisms of Bacterial …, 2016 - Wiley Online Library
Many pathogenic bacteria transit between free‐living lifestyles and the markedly different
environments presented by their hosts. This requires detection, integration, and response to …
environments presented by their hosts. This requires detection, integration, and response to …
Small and smaller—sRNAs and microRNAs in the regulation of toxin gene expression in prokaryotic cells: a mini-review
S Bloch, A Węgrzyn, G Węgrzyn, B Nejman-Faleńczyk - Toxins, 2017 - mdpi.com
Non-coding small RNAs (sRNAs) have been identified in the wide range of bacteria (also
pathogenic species) and found to play an important role in the regulation of many …
pathogenic species) and found to play an important role in the regulation of many …