Emerging technologies and their impact on regulatory science

E Anklam, MI Bahl, R Ball, RD Beger… - Experimental …, 2022 - journals.sagepub.com
There is an evolution and increasing need for the utilization of emerging cellular, molecular
and in silico technologies and novel approaches for safety assessment of food, drugs, and …

Cardiovascular toxicities of CAR T-cell therapy

NP Patel, PG Doukas, LI Gordon, N Akhter - Current oncology reports, 2021 - Springer
Purpose of review This review provides a contemporary overview of current studies outlining
the incidence and characteristics of CAR T-cell cardiotoxicity in an effort to identify future …

[HTML][HTML] Artificial intelligence opportunities in cardio-oncology: Overview with spotlight on electrocardiography

DSL Martinez, PA Noseworthy, O Akbilgic… - American heart journal …, 2022 - Elsevier
Cardiovascular disease is a leading cause of death among cancer survivors, second only to
cancer recurrence or development of new tumors. Cardio-oncology has therefore emerged …

MRI in cardio‐oncology: A review of cardiac complications in oncologic care

D Jeong, G Gladish, T Chitiboi… - Journal of Magnetic …, 2019 - Wiley Online Library
From detailed characterization of cardiac abnormalities to the assessment of cancer
treatment‐related cardiac dysfunction, cardiac MRI is playing a growing role in the …

The lethal effects and determinants of microcystin-LR on heart: A mini review

M Alosman, L Cao, IY Massey, F Yang - Toxin reviews, 2021 - Taylor & Francis
Microcystin-leucine arginine (MC-LR) is the most common microcystin (MC) variant
produced during cyanobacteria blooms. Chronic and acute exposure to MC-LR is known to …

[HTML][HTML] The impact of exercise on cardiotoxicity in pediatric and adolescent cancer survivors: a scoping review

SJ Kendall, JE Langley, M Aghdam, BN Crooks… - Current …, 2022 - mdpi.com
Childhood and adolescent cancer survivors are disproportionately more likely to develop
cardiovascular diseases from the late effects of cardiotoxic therapies (eg, anthracycline …

[HTML][HTML] Quantitative assessment of radiotherapy-induced myocardial damage using MRI: A systematic review

A Omidi, E Weiss, CR Trankle, M Rosu-Bubulac… - Cardio-Oncology, 2023 - Springer
Purpose To determine the role of magnetic resonance imaging (MRI)-based metrics to
quantify myocardial toxicity following radiotherapy (RT) in human subjects through review of …

Alterations in left atrial strain in breast cancer patients immediately post anthracycline exposure

P Emerson, L Stefani, A Boyd, D Richards, R Hui… - Heart, Lung and …, 2024 - Elsevier
Aims With improved diagnosis and treatments, a greater percentage of breast cancer
patients are achieving long-term survival. Consequently, long-term cardiotoxicity secondary …

[HTML][HTML] Pediatric chemotherapy drugs associated with cardiotoxicity

G Hitawala, E Jain, L Castellanos, R Garimella, R Akku… - Cureus, 2021 - ncbi.nlm.nih.gov
Pediatric cancers are a common cause of childhood morbidity. As a result,
chemotherapeutic regimens have been designed to target childhood cancers. These …

[HTML][HTML] Chemotherapy-induced Cardiac18F-FDG Uptake in Patients with Lymphoma: An Early Metabolic Index of Cardiotoxicity?

MLC Dourado, LT Dompieri, GM Leitão… - Arquivos Brasileiros …, 2022 - SciELO Brasil
Background: It is uncertain whether myocardial fluorodeoxyglucose uptake occurs solely
due to physiological features or if it represents a metabolic disarrangement under …