[HTML][HTML] Therapeutics targeting angiogenesis: genetics and epigenetics, extracellular miRNAs and signaling networks

M Katoh - International journal of molecular medicine, 2013 - spandidos-publications.com
Angiogenesis is a process of neovascular formation from pre-existing blood vessels, which
consists of sequential steps for vascular destabilization, angiogenic sprouting, lumen …

Challenges in elucidating the genetics of diabetic retinopathy

JZ Kuo, TY Wong, JI Rotter - JAMA ophthalmology, 2014 - jamanetwork.com
Importance In the past decade, significant progress in genomic medicine and technologic
developments has revolutionized our approach to common complex disorders in many …

Association between the vascular endothelial growth factor single nucleotide polymorphisms and diabetic retinopathy risk: A meta‐analysis: 关于血管内皮生长因子单 …

XJ Xie, YM Yang, JK Jiang, YQ Lu - Journal of Diabetes, 2017 - Wiley Online Library
背景这项研究的目的是揭示血管内皮生长因子(vascular endothelial growth factor, VEGF)
单核苷酸多态性(single nucleotide polymorphisms, SNPs) 和糖尿病视网膜病变(diabetes …

VEGF and VEGFR genotyping in the prediction of clinical outcome for HCC patients receiving sorafenib: The ALICE‐1 study

M Scartozzi, L Faloppi… - … journal of cancer, 2014 - Wiley Online Library
Although new treatment modalities changed the global approach to hepatocellular
carcinoma (HCC), this disease still represents a medical challenge. Currently, the …

[HTML][HTML] Effect of serum cytokines and VEGF levels on diabetic retinopathy and macular thickness

BT Ozturk, B Bozkurt, H Kerimoglu, M Okka… - Molecular …, 2009 - ncbi.nlm.nih.gov
Purpose To investigate the role of serum inflammatory cytokines and vascular endothelial
growth factor (VEGF) in diabetic retinopathy (DR) and evaluate their relationship with …

Do genomic factors play a role in diabetic retinopathy?

AP Cabrera, F Monickaraj, S Rangasamy… - Journal of clinical …, 2020 - mdpi.com
Although there is strong clinical evidence that the control of blood glucose, blood pressure,
and lipid level can prevent and slow down the progression of diabetic retinopathy (DR) as …

Six novel loci associated with circulating VEGF levels identified by a meta-analysis of genome-wide association studies

SH Choi, D Ruggiero, R Sorice, C Song, T Nutile… - PLoS …, 2016 - journals.plos.org
Vascular endothelial growth factor (VEGF) is an angiogenic and neurotrophic factor,
secreted by endothelial cells, known to impact various physiological and disease processes …

Identification of cis- and trans-Acting Genetic Variants Explaining Up to Half the Variation in Circulating Vascular Endothelial Growth Factor Levels

S Debette, S Visvikis-Siest, MH Chen… - Circulation …, 2011 - Am Heart Assoc
Rationale: Vascular endothelial growth factor (VEGF) affects angiogenesis, atherosclerosis,
and cancer. Although the heritability of circulating VEGF levels is high, little is known about …

The associations between VEGF gene polymorphisms and diabetic retinopathy susceptibility: a meta‐analysis of 11 case‐control studies

L Han, L Zhang, W Xing, R Zhuo, XL Lin… - Journal of diabetes …, 2014 - Wiley Online Library
Aims. Published data on the associations of VEGF polymorphisms with diabetic retinopathy
(DR) susceptibility are inconclusive. A systematic meta‐analysis was undertaken to clarify …

VEGF and VEGFR polymorphisms affect clinical outcome in advanced renal cell carcinoma patients receiving first-line sunitinib

M Scartozzi, M Bianconi, L Faloppi, C Loretelli… - British journal of …, 2013 - nature.com
Background: Currently, sunitinib represents one of the therapeutic strongholds for renal cell
carcinoma, but the criteria for treatment selection are lacking. We assessed the role of …