Brain-derived neurotrophic factor in Alzheimer's disease and its pharmaceutical potential
L Gao, Y Zhang, K Sterling, W Song - Translational neurodegeneration, 2022 - Springer
Synaptic abnormalities are a cardinal feature of Alzheimer's disease (AD) that are known to
arise as the disease progresses. A growing body of evidence suggests that pathological …
arise as the disease progresses. A growing body of evidence suggests that pathological …
The spiral ganglion: connecting the peripheral and central auditory systems
In mammals, the initial bridge between the physical world of sound and perception of that
sound is established by neurons of the spiral ganglion. The cell bodies of these neurons …
sound is established by neurons of the spiral ganglion. The cell bodies of these neurons …
Auditory-nerve responses to varied inter-phase gap and phase duration of the electric pulse stimulus as predictors for neuronal degeneration
After severe hair cell loss, secondary degeneration of spiral ganglion cells (SGCs) is
observed—a gradual process that spans years in humans but only takes weeks in guinea …
observed—a gradual process that spans years in humans but only takes weeks in guinea …
The role of BDNF as a biomarker in cognitive and sensory neurodegeneration
A Pisani, F Paciello, V Del Vecchio, R Malesci… - Journal of Personalized …, 2023 - mdpi.com
Brain-derived neurotrophic factor (BDNF) has a crucial function in the central nervous
system and in sensory structures including olfactory and auditory systems. Many studies …
system and in sensory structures including olfactory and auditory systems. Many studies …
Close-field electroporation gene delivery using the cochlear implant electrode array enhances the bionic ear
JL Pinyon, SF Tadros, KE Froud, AC Y. Wong… - Science translational …, 2014 - science.org
The cochlear implant is the most successful bionic prosthesis and has transformed the lives
of people with profound hearing loss. However, the performance of the “bionic ear” is still …
of people with profound hearing loss. However, the performance of the “bionic ear” is still …
New molecular therapies for the treatment of hearing loss
An estimated 466 million people suffer from hearing loss worldwide. Sensorineural hearing
loss is characterized by degeneration of key structures of the sensory pathway in the …
loss is characterized by degeneration of key structures of the sensory pathway in the …
From molecular to nanotechnology strategies for delivery of neurotrophins: emphasis on brain-derived neurotrophic factor (BDNF)
C Géral, A Angelova, S Lesieur - Pharmaceutics, 2013 - mdpi.com
Neurodegenerative diseases represent a major public health problem, but beneficial clinical
treatment with neurotrophic factors has not been established yet. The therapeutic use of …
treatment with neurotrophic factors has not been established yet. The therapeutic use of …
A microelectromechanical system artificial basilar membrane based on a piezoelectric cantilever array and its characterization using an animal model
We proposed a piezoelectric artificial basilar membrane (ABM) composed of a
microelectromechanical system cantilever array. The ABM mimics the tonotopy of the …
microelectromechanical system cantilever array. The ABM mimics the tonotopy of the …
Biomaterial-based drug delivery systems for the controlled release of neurotrophic factors
NK Mohtaram, A Montgomery, SM Willerth - Biomedical materials, 2013 - iopscience.iop.org
This review highlights recent work on the use of biomaterial-based drug delivery systems to
control the release of neurotrophic factors as a potential strategy for the treatment of …
control the release of neurotrophic factors as a potential strategy for the treatment of …
A Triboelectric-Based Artificial Basilar Membrane to Mimic Cochlear Tonotopy.
A Triboelectric-Based Artificial Basilar Membrane to Mimic Cochlear Tonotopy. - Abstract -
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Europe PMC Sign in | Create an account https://orcid.org Europe PMC Menu About Tools …