Cryptochromes are flavoprotein photoreceptors first identified in Arabidopsis thaliana, where
they play key roles in growth and development. Subsequently identified in prokaryotes …

The circadian clock mechanism in mammals involves two interlocking transcriptional
feedback loops. Rev-erb α, through its role as a transcriptional repressor, was thought to be …

For many years, neurons of the suprachiasmatic nucleus (SCN) in the hypothalamus were
thought to contain the unique mammalian clock controlling circadian rhythmicity of …

CRYPTOCHROME (CRY) is the primary circadian photoreceptor in Drosophila. We show
that CRY binding to TIMELESS (TIM) is light-dependent in flies and irreversibly commits TIM …

The brain's biological clock, which, in mammals, is located in the suprachiasmatic nucleus
(SCN), generates circadian rhythms in behaviour and physiology. These biological rhythms …

Recent research on the circadian system of the zebrafish is reviewed. This teleost has
become an attractive model system because of its advantages for genetic analyses …

The posttranscriptional mechanisms that control the cycling of circadian clock protein levels
are not known. Here we demonstrate a role for protein phosphatase 2A (PP2A) in the cyclic …

Cryptochromes have been suggested to be the primary magnetoreceptor molecules
underlying light-dependent magnetic compass detection in migratory birds. Here we review …

Drosophila melanogaster display overt circadian rhythms in rest: activity behavior and
eclosion. These rhythms have an endogenous period of approximately 24 hr and can adjust …

Background: Circadian clocks are synchronized by both light: dark cycles and by
temperature fluctuations. Although it has long been known that temperature cycles can …