Abstract Objectives The European Society for Clinical and Economic Aspects of
Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) sought to revisit the …

Osteoarthritis (OA) is a degenerative joint disease characterized by progressive cartilage
degradation but also synovial membrane inflammation, osteophyte formation and …

Intra-articular drug delivery has a number of advantages over systemic administration;
however, for the past 20 years, intra-articular treatment options for the management of knee …

Knee osteoarthritis (OA) is a leading cause of pain and disability. Although conventional
treatments show modest benefits, pilot and phase I/II trials with bone marrow (BM) and …

Objective To evaluate the effectiveness and safety of viscosupplementation for pain and
function in patients with knee osteoarthritis. Design Systematic review and meta-analysis of …

Background: The relative efficacy of available treatments of knee osteoarthritis (OA) must be
determined for rational treatment algorithms to be formulated. Purpose: To examine the …

Macrophages exhibit phenotypic diversity permitting wide-ranging roles in maintaining
physiologic homeostasis. Hyaluronic acid, a major glycosaminoglycan of the extracellular …

Osteoarthritis is a debilitating disease that has increased in prevalence across the world due
to the aging population. Currently, physicians use a plethora of treatment strategies to try …

Background Knee osteoarthritis (OA) is one of the leading causes of disability within the
adult population. Current treatment options for OA of the knee include intra-articular (IA) …

Osteoarthritis is thought to be the most prevalent chronic joint disease. The incidence of
osteoarthritis is rising because of the ageing population and the epidemic of obesity. Pain …