Covering: 1998 to 2011. Previous review: Nat. Prod. Rep., 1998, 15, 173–186The fourteen
years that have passed since the previous review on this topic have seen a significant …

A novel and specific liquid chromatography–tandem mass spectrometric method (LC–
MS/MS) was developed and validated for the quantification of hydroxychloroquine in human …

High-performance liquid chromatography–tandem mass spectrometry (LC–MS/MS) is a
standard analytical technique for therapeutic drug monitoring (TDM). A rapid LC–MS/MS …

The advent of HIV-Integrase inhibitors (IN) has marked a significant impact on the lives of
HIV patients. Since the launch of the first anti retro-viral drug “Azidothymidine” to the recent …

Therapeutic drug monitoring (TDM) is essential in the optimization of antiretroviral (ARV)
treatments. In this work, we describe a new method for the simultaneous quantification of six …

Raltegravir is a potent inhibitor of HIV integrase. Persistently high intracellular
concentrations of raltegravir may explain sustained efficacy despite high pharmacokinetic …

HIV-1 integrase strand transfer inhibitors are an important class of compounds targeted for
the treatment of HIV-1 infection. Microdosing has emerged as an attractive tool to assist in …

A sensitive analytical method has been developed and validated for the quantification of L‐
ergothioneine in human plasma and erythrocytes by liquid chromatography‐tandem mass …

We aim to evaluate the influence of covariates, including cytochrome P450 3A (CYP3A)
genetic polymorphisms, on the pharmacokinetics of midazolam (MDZ) in Asian cancer …

Introduction: Efavirenz is an inducer of drug metabolism enzymes. We studied the effect of
efavirenz and ritonavir-boosted darunavir on serum unconjugated and conjugated bilirubin …