Fertility preservation: the challenge of freezing and transplanting ovarian tissue

MM Dolmans, J Donnez, L Cacciottola - Trends in molecular medicine, 2021 - cell.com
Cancer treatments are increasingly effective, but can result in iatrogenic premature ovarian
insufficiency. Ovarian tissue cryopreservation is the only option available to preserve fertility …

Ovarian tissue cryopreservation and transplantation: a review

J Donnez, B Martinez-Madrid, P Jadoul… - Human reproduction …, 2006 - academic.oup.com
The review covers current options for ovarian tissue cryopreservation and transplantation
and provides a systematic review of the existing literature from the last 10 years, taking into …

Autologous grafting of cryopreserved prepubertal rhesus testis produces sperm and offspring

AP Fayomi, K Peters, M Sukhwani, H Valli-Pulaski… - Science, 2019 - science.org
Testicular tissue cryopreservation is an experimental method to preserve the fertility of
prepubertal patients before they initiate gonadotoxic therapies for cancer or other conditions …

Orthotopic and heterotopic ovarian tissue transplantation

I Demeestere, P Simon, S Emiliani… - Human reproduction …, 2009 - academic.oup.com
BACKGROUND Transplantation of ovarian tissue is, at present, the only clinical option
available to restore fertility using cryopreserved ovarian tissue. More than 30 …

[HTML][HTML] A new step toward the artificial ovary: survival and proliferation of isolated murine follicles after autologous transplantation in a fibrin scaffold

V Luyckx, MM Dolmans, J Vanacker, C Legat… - Fertility and sterility, 2014 - Elsevier
Objective To create an artificial ovary to provide an alternative way of restoring fertility in
patients who cannot benefit from transplantation of cryopreserved ovarian tissue due to the …

[HTML][HTML] Electron paramagnetic resonance as a tool to evaluate human ovarian tissue reoxygenation after xenografting

AS Van Eyck, BF Jordan, B Gallez, JF Heilier… - Fertility and sterility, 2009 - Elsevier
OBJECTIVE: To develop electron paramagnetic resonance (EPR) oximetry as a tool to
characterize the oxygen environment in human ovarian xenografts in the early postgrafting …

[HTML][HTML] Both host and graft vessels contribute to revascularization of xenografted human ovarian tissue in a murine model

AS Van Eyck, C Bouzin, O Feron, L Romeu… - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To characterize the human ovarian xenograft revascularization process.
DESIGN: Prospective experimental study. SETTING: Gynecology research unit in a …

Vitrification preserves proliferation capacity in human spermatogonia

J Poels, A Van Langendonckt, MC Many… - Human …, 2013 - academic.oup.com
STUDY QUESTION Does vitrification of human immature testicular tissue (ITT) have
potential benefits for future fertility preservation? Does vitrification of human ITT have …

[HTML][HTML] Live birth after ovarian tissue autograft in a patient with sickle cell disease treated by allogeneic bone marrow transplantation

C Roux, C Amiot, G Agnani, Y Aubard, PS Rohrlich… - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To report the first case of restoration of ovarian activity and live birth after
cryopreserved ovarian tissue autograft in a patient without cancer treated by allogeneic …

Diethylhexyl phthalate exposure impairs follicular development and affects oocyte maturation in the mouse

XF Zhang, LJ Zhang, L Li, YN Feng… - Environmental and …, 2013 - Wiley Online Library
Diethylhexyl phthalate (DEHP) is an estrogen‐like compound widely used as a commercial
plasticizer and present in medical devices, tubing, food containers and packaging. It is …